ID   Mel Mtp
AC   CVCL_B6KG
SY   mel Mtp; Mel MTP
DR   cancercelllines; CVCL_B6KG
DR   Wikidata; Q112129304
RX   CelloPub=CLPUB00680;
RX   CelloPub=CLPUB00681;
RX   Patent=RU2360963;
RX   PubMed=16107020;
RX   PubMed=30551515;
CC   Group: Patented cell line.
CC   Registration: Non-internationally recognized Depositary Authority, Russian Cell Culture Collection (RCCC); 705D.
CC   Sequence variation: Mutation; HGNC; 7989; NRAS; Simple; p.Gln61Lys (c.181C>A); ClinVar=VCV000073058; Zygosity=Unspecified (CelloPub=CLPUB00680; PubMed=30551515).
CC   Derived from site: Metastatic; Right axillary lymph node; UBERON=UBERON_0001097.
DI   NCIt; C3224; Melanoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
CA   Cancer cell line
DT   Created: 17-03-22; Last updated: 05-10-23; Version: 5
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RX   CelloPub=CLPUB00680;
RA   Mikhailova I.N., Baryshnikov A.Y., Morozova L.F., Burova O.S.,
RA   Shubina I.Z., Kovalevsky D.A., Voronina E.S., Treshalina H.M.,
RA   Lushnikova A.A., Tsyganova I.V., Mazurenko N.N.;
RT   "Human skin melanoma cell lines collection.";
RL   (In) Management of malignant melanoma; None X. (eds.); pp.6.1-6.6; SM Group; Dover (2016).
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RX   CelloPub=CLPUB00681;
RA   Berezhnoy A.E., Zakeyeva I.R., Kibardin A.V., Chernysheva A.D.,
RA   Moiseyenko V.M., Danilov A.O., Demidov L.V., Baryshnikov A.Y.,
RA   Gnuchev N.V., Georgiev G.P., Larin S.S.;
RT   "Analysis of HLA-E expression in human melanoma cells.";
RL   Ross. Bioterap. Zh. 5:66-71(2006).
//
RX   Patent=RU2360963;
RA   Mikhailova I.N., Baryshnikov A.Y., Demidov L.V., Kiselev S.L.,
RA   Burova O.S., Morozova L.F.;
RT   "Cell line of human melanoma mel Mtp used for making anticancer
RT   vaccines.";
RL   Patent number RU2360963, 10-Jul-2009.
//
RX   PubMed=16107020;
RA   Mikhailova I.N., Lukashina M.I., Baryshnikov A.Y., Morozova L.F.,
RA   Burova O.S., Palkina T.N., Kozlov A.M., Golubeva V.A.,
RA   Cheremushkin E.A., Doroshenko M.B., Demidov L.V., Kiselev S.L.,
RA   Larin S.S., Georgiev G.P.;
RT   "Melanoma cell lines as the basis for antitumor vaccine preparation.";
RL   Vestn. Ross. Akad. Med. Nauk 2005:37-40(2005).
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RX   PubMed=30551515; DOI=10.1016/j.biopha.2018.11.109;
RA   Ryabaya O., Prokofieva A., Akasov R., Khochenkov D., Emelyanova M.,
RA   Burov S., Markvicheva E., Inshakov A., Stepanova E.V.;
RT   "Metformin increases antitumor activity of MEK inhibitor binimetinib
RT   in 2D and 3D models of human metastatic melanoma cells.";
RL   Biomed. Pharmacother. 109:2548-2560(2019).
//