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Cellosaurus Mel Ibr (CVCL_B6JK)

[Text version]
Cell line name Mel Ibr
Synonyms mel Ibr; Mel IBR
Accession CVCL_B6JK
Resource Identification Initiative To cite this cell line use: Mel Ibr (RRID:CVCL_B6JK)
Comments Group: Patented cell line.
Registration: Non-internationally recognized Depositary Authority, Russian Cell Culture Collection (RCCC); 689D.
Derived from site: Metastatic; Hypodermis; UBERON=UBERON_0002072.
Sequence variations
  • Mutation; HGNC; 1097; BRAF; Simple; p.Val600Glu (c.1799T>A); ClinVar=VCV000013961; Zygosity=Unspecified (CelloPub=CLPUB00680; PubMed=28881731).
Disease Cutaneous melanoma (NCIt: C3510)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_B6KC (Mel Ibr subclone)CVCL_B6L2 (Mel IG)
Sex of cell Female
Category Cancer cell line
Publications

PubMed=16107020
Mikhailova I.N., Lukashina M.I., Baryshnikov A.Y., Morozova L.F., Burova O.S., Palkina T.N., Kozlov A.M., Golubeva V.A., Cheremushkin E.A., Doroshenko M.B., Demidov L.V., Kiselev S.L., Larin S.S., Georgiev G.P.
Melanoma cell lines as the basis for antitumor vaccine preparation.
Vestn. Ross. Akad. Med. Nauk 2005:37-40(2005)

CLPUB00681
Berezhnoy A.E., Zakeyeva I.R., Kibardin A.V., Chernysheva A.D., Moiseyenko V.M., Danilov A.O., Demidov L.V., Baryshnikov A.Y., Gnuchev N.V., Georgiev G.P., Larin S.S.
Analysis of HLA-E expression in human melanoma cells.
Ross. Bioterap. Zh. 5:66-71(2006)

Patent=RU2287576
Mikhailova I.N., Baryshnikov A.Y., Morozova L.F., Berezhnoy A.E., Kozlov A.M., Larin S.S., Georgiev G.P., Vorozhtsov G.N., Gnuchev N.V.
Human melanoma cellular line mel Ibr used in preparing antitumor vaccine.
Patent number RU2287576, 20-Nov-2006

PubMed=18781128; DOI=10.1097/CMR.0b013e32830e391d
Mikhailova I.N., Kovalevsky D.A., Morozova L.F., Golubeva V.A., Cheremushkin E.A., Lukashina M.I., Voronina E.S., Burova O.S., Utyashev I.A., Kiselev S.L., Demidov L.V., Beabealashvilli R.S., Baryshnikov A.Y.
Cancer/testis genes expression in human melanoma cell lines.
Melanoma Res. 18:303-313(2008)

PubMed=26388567; DOI=10.1007/s10517-015-3007-5
Suraeva N.M., Morozova L.F., Samoilov A.V., Burova O.S., Golubeva V.A., Baryshnikova M.A., Baryshnikov A.Y.
Changes in the morphological and immunological characteristics of Mel Ibr melanoma cells in response to chicken embryo extract.
Bull. Exp. Biol. Med. 159:520-523(2015)

CLPUB00680
Mikhailova I.N., Baryshnikov A.Y., Morozova L.F., Burova O.S., Shubina I.Z., Kovalevsky D.A., Voronina E.S., Treshalina H.M., Lushnikova A.A., Tsyganova I.V., Mazurenko N.N.
Human skin melanoma cell lines collection.
(In) Management of malignant melanoma; pp.1-6; SM Group; Dover (2016)

PubMed=28726209; DOI=10.1007/s10517-017-3778-y
Suraeva N.M., Morozova L.F., Ryabaya O.O., Khochenkova Y.A., Samoilov A.V., Burova O.S., Golubtsova N.V., Barmashov A.E., Baryshnikova M.A.
Characteristics of Mel Ibr melanoma line subclone after treatment with chicken embryo extract.
Bull. Exp. Biol. Med. 163:255-259(2017)

PubMed=28881731; DOI=10.18632/oncotarget.17014
Emelyanova M., Ghukasyan L., Abramov I., Ryabaya O., Stepanova E.V., Kudryavtseva A., Sadritdinova A., Dzhumakova C., Belysheva T., Surzhikov S., Lyubchenko L., Zasedatelev A., Nasedkina T.
Detection of BRAF, NRAS, KIT, GNAQ, GNA11 and MAP2K1/2 mutations in Russian melanoma patients using LNA PCR clamp and biochip analysis.
Oncotarget 8:52304-52320(2017)

DOI=10.17650/1726-9784-2018-17-4-27-35
Mikhailova I.N., Treshalina E.M., Morozova L.F., Andronova N.V., Shubina I.Z., Lushnikova A.A.
Cell lines of human melanoma and their xenograft with BRAF or NRAS mutations a targets for targeted therapy.
Ross. Bioterap. Zh. 17:27-35(2018)

Cross-references
Cell line databases/resources cancercelllines; CVCL_B6JK
Encyclopedic resources Wikidata; Q112129270
Entry history
Entry creation17-Mar-2022
Last entry update05-Oct-2023
Version number5