ID   Mel Ibr
AC   CVCL_B6JK
SY   mel Ibr; Mel IBR
DR   cancercelllines; CVCL_B6JK
DR   Wikidata; Q112129270
RX   CelloPub=CLPUB00680;
RX   CelloPub=CLPUB00681;
RX   DOI=10.17650/1726-9784-2018-17-4-27-35;
RX   Patent=RU2287576;
RX   PubMed=16107020;
RX   PubMed=18781128;
RX   PubMed=26388567;
RX   PubMed=28726209;
RX   PubMed=28881731;
CC   Group: Patented cell line.
CC   Registration: Non-internationally recognized Depositary Authority, Russian Cell Culture Collection (RCCC); 689D.
CC   Sequence variation: Mutation; HGNC; 1097; BRAF; Simple; p.Val600Glu (c.1799T>A); ClinVar=VCV000013961; Zygosity=Unspecified (CelloPub=CLPUB00680; PubMed=28881731).
CC   Derived from site: Metastatic; Hypodermis; UBERON=UBERON_0002072.
DI   NCIt; C3510; Cutaneous melanoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Female
CA   Cancer cell line
DT   Created: 17-03-22; Last updated: 05-10-23; Version: 5
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RX   CelloPub=CLPUB00680;
RA   Mikhailova I.N., Baryshnikov A.Y., Morozova L.F., Burova O.S.,
RA   Shubina I.Z., Kovalevsky D.A., Voronina E.S., Treshalina H.M.,
RA   Lushnikova A.A., Tsyganova I.V., Mazurenko N.N.;
RT   "Human skin melanoma cell lines collection.";
RL   (In) Management of malignant melanoma; pp.1-6; SM Group; Dover (2016).
//
RX   CelloPub=CLPUB00681;
RA   Berezhnoy A.E., Zakeyeva I.R., Kibardin A.V., Chernysheva A.D.,
RA   Moiseyenko V.M., Danilov A.O., Demidov L.V., Baryshnikov A.Y.,
RA   Gnuchev N.V., Georgiev G.P., Larin S.S.;
RT   "Analysis of HLA-E expression in human melanoma cells.";
RL   Ross. Bioterap. Zh. 5:66-71(2006).
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RX   DOI=10.17650/1726-9784-2018-17-4-27-35;
RA   Mikhailova I.N., Treshalina E.M., Morozova L.F., Andronova N.V.,
RA   Shubina I.Z., Lushnikova A.A.;
RT   "Cell lines of human melanoma and their xenograft with BRAF or NRAS
RT   mutations a targets for targeted therapy.";
RL   Ross. Bioterap. Zh. 17:27-35(2018).
//
RX   Patent=RU2287576;
RA   Mikhailova I.N., Baryshnikov A.Y., Morozova L.F., Berezhnoy A.E.,
RA   Kozlov A.M., Larin S.S., Georgiev G.P., Vorozhtsov G.N., Gnuchev N.V.;
RT   "Human melanoma cellular line mel Ibr used in preparing antitumor
RT   vaccine.";
RL   Patent number RU2287576, 20-Nov-2006.
//
RX   PubMed=16107020;
RA   Mikhailova I.N., Lukashina M.I., Baryshnikov A.Y., Morozova L.F.,
RA   Burova O.S., Palkina T.N., Kozlov A.M., Golubeva V.A.,
RA   Cheremushkin E.A., Doroshenko M.B., Demidov L.V., Kiselev S.L.,
RA   Larin S.S., Georgiev G.P.;
RT   "Melanoma cell lines as the basis for antitumor vaccine preparation.";
RL   Vestn. Ross. Akad. Med. Nauk 2005:37-40(2005).
//
RX   PubMed=18781128; DOI=10.1097/CMR.0b013e32830e391d;
RA   Mikhailova I.N., Kovalevsky D.A., Morozova L.F., Golubeva V.A.,
RA   Cheremushkin E.A., Lukashina M.I., Voronina E.S., Burova O.S.,
RA   Utyashev I.A., Kiselev S.L., Demidov L.V., Beabealashvilli R.S.,
RA   Baryshnikov A.Y.;
RT   "Cancer/testis genes expression in human melanoma cell lines.";
RL   Melanoma Res. 18:303-313(2008).
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RX   PubMed=26388567; DOI=10.1007/s10517-015-3007-5;
RA   Suraeva N.M., Morozova L.F., Samoilov A.V., Burova O.S.,
RA   Golubeva V.A., Baryshnikova M.A., Baryshnikov A.Y.;
RT   "Changes in the morphological and immunological characteristics of Mel
RT   Ibr melanoma cells in response to chicken embryo extract.";
RL   Bull. Exp. Biol. Med. 159:520-523(2015).
//
RX   PubMed=28726209; DOI=10.1007/s10517-017-3778-y;
RA   Suraeva N.M., Morozova L.F., Ryabaya O.O., Khochenkova Y.A.,
RA   Samoilov A.V., Burova O.S., Golubtsova N.V., Barmashov A.E.,
RA   Baryshnikova M.A.;
RT   "Characteristics of Mel Ibr melanoma line subclone after treatment
RT   with chicken embryo extract.";
RL   Bull. Exp. Biol. Med. 163:255-259(2017).
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RX   PubMed=28881731; DOI=10.18632/oncotarget.17014;
RA   Emelyanova M., Ghukasyan L., Abramov I., Ryabaya O., Stepanova E.V.,
RA   Kudryavtseva A., Sadritdinova A., Dzhumakova C., Belysheva T.,
RA   Surzhikov S., Lyubchenko L., Zasedatelev A., Nasedkina T.;
RT   "Detection of BRAF, NRAS, KIT, GNAQ, GNA11 and MAP2K1/2 mutations in
RT   Russian melanoma patients using LNA PCR clamp and biochip analysis.";
RL   Oncotarget 8:52304-52320(2017).
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