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Cellosaurus STPDLDS (CVCL_B6BN)

[Text version]
Cell line name STPDLDS
Synonyms SV40T-Ag and TERT immortalized PerioDontal Ligament Down Syndrome cells
Accession CVCL_B6BN
Resource Identification Initiative To cite this cell line use: STPDLDS (RRID:CVCL_B6BN)
Comments Population: Japanese.
Karyotypic information: Has a large number of abnormal chromosomes (PubMed=34590290).
Genetic integration: Method=Transfection; Gene=HGNC; HGNC:11730; TERT.
Genetic integration: Method=Transfection; Gene=UniProtKB; P13249; S.alboniger pac (PuroR).
Genetic integration: Method=Transfection; Gene=UniProtKB; P03070; SV40 large T antigen.
Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Transposon Tn5 neo.
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40).
Derived from site: In situ; Tooth, periodontal ligament; UBERON=UBERON_0008266.
Cell type: Fibroblast of periodontal ligament; CL=CL_2000017.
Disease Down syndrome (NCIt: C2993)
Down syndrome (ORDO: Orphanet_870)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 11Y
Category Transformed cell line
STR profile Source(s): PubMed=34590290

Markers:
AmelogeninX
CSF1PO11,12
D5S81810,13
D7S82010
D13S3178,12
D16S53911,14
D21S1129,31.2
TH019,9.3
TPOX11
vWA17,18

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Publications

PubMed=34590290; DOI=10.1007/s13577-021-00621-0; PMCID=PMC8732922
Asakawa T., Yamada A., Kugino M., Hasegawa T., Yoshimura K., Sasa K., Kinoshita M., Nitta M., Nagata K., Sugiyama T., Kamijo R., Funatsu T.
Establishment of Down's syndrome periodontal ligament cells by transfection with SV40T-Ag and hTERT.
Hum. Cell 35:379-383(2022)

Cross-references
Encyclopedic resources Wikidata; Q112041738
Entry history
Entry creation17-Mar-2022
Last entry update10-Apr-2025
Version number7