ID   STPDLDS
AC   CVCL_B6BN
SY   SV40T-Ag and TERT immortalized PerioDontal Ligament Down Syndrome cells
DR   Wikidata; Q112041738
RX   PubMed=34590290;
CC   Population: Japanese.
CC   Karyotypic information: Has a large number of abnormal chromosomes (PubMed=34590290).
CC   Genetic integration: Method=Transfection; Gene=HGNC; HGNC:11730; TERT.
CC   Genetic integration: Method=Transfection; Gene=UniProtKB; P13249; S.alboniger pac (PuroR).
CC   Genetic integration: Method=Transfection; Gene=UniProtKB; P03070; SV40 large T antigen.
CC   Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Transposon Tn5 neo.
CC   Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40).
CC   Derived from site: In situ; Tooth, periodontal ligament; UBERON=UBERON_0008266.
CC   Cell type: Fibroblast of periodontal ligament; CL=CL_2000017.
ST   Source(s): PubMed=34590290
ST   Amelogenin: X
ST   CSF1PO: 11,12
ST   D13S317: 8,12
ST   D16S539: 11,14
ST   D21S11: 29,31.2
ST   D5S818: 10,13
ST   D7S820: 10
ST   TH01: 9,9.3
ST   TPOX: 11
ST   vWA: 17,18
DI   NCIt; C2993; Down syndrome
DI   ORDO; Orphanet_870; Down syndrome
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
AG   11Y
CA   Transformed cell line
DT   Created: 17-03-22; Last updated: 10-04-25; Version: 7
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RX   PubMed=34590290; DOI=10.1007/s13577-021-00621-0; PMCID=PMC8732922;
RA   Asakawa T., Yamada A., Kugino M., Hasegawa T., Yoshimura K., Sasa K.,
RA   Kinoshita M., Nitta M., Nagata K., Sugiyama T., Kamijo R.,
RA   Funatsu T.;
RT   "Establishment of Down's syndrome periodontal ligament cells by
RT   transfection with SV40T-Ag and hTERT.";
RL   Hum. Cell 35:379-383(2022).
//