Cellosaurus WAe009-A-R (CVCL_B5ZI)
| Cell line name | WAe009-A-R |
|---|---|
| Synonyms | WA09 NRL+/eGFP; H9-NRL-GP |
| Accession | CVCL_B5ZI |
| Resource Identification Initiative | To cite this cell line use: WAe009-A-R (RRID:CVCL_B5ZI) |
| Comments | Characteristics: Valuable tool for studying human rod development and disease and testing therapeutic strategies for retinitis pigmentosa (PubMed=29402929). Characteristics: Using CRISPR/Cas9 a single allele of NRL was replaced with an eGFP reporter gene (PubMed=29402929). Knockout cell: Method=CRISPR/Cas9; HGNC; 8002; NRL (Note=1 of 2 alleles). Genetic integration: Method=CRISPR/Cas9; Gene=FPbase; R9NL8; eGFP (Note=Enhanced GFP). Derived from site: In situ; Blastocyst; UBERON=UBERON_0000358. Cell type: Embryonic stem cell; CL=CL_0002322. |
| Species of origin | Homo sapiens (Human) (NCBI Taxonomy: 9606) |
| Hierarchy | Parent: CVCL_9773 (WA09) |
| Sex of cell | Female |
| Age at sampling | Blastocyst stage |
| Category | Embryonic stem cell |
| Publications | PubMed=29402929; DOI=10.1038/s41598-018-20813-3; PMCID=PMC5799252 |
| Cross-references | |
| Cell line databases/resources | hPSCreg; WAe009-A-R |
| Biological sample resources | BioSamples; SAMEA113967375 |
| Encyclopedic resources | Wikidata; Q112041918 |
| Entry history | |
| Entry creation | 17-Mar-2022 |
| Last entry update | 10-Sep-2024 |
| Version number | 7 |