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Cellosaurus U2OS tGFP-ADCYAP1R1 (CVCL_B5WM)

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Cell line name U2OS tGFP-ADCYAP1R1
Synonyms ADCYAP1R1-tGFP_U2OS; PAC1-tGFP
Accession CVCL_B5WM
Resource Identification Initiative To cite this cell line use: U2OS tGFP-ADCYAP1R1 (RRID:CVCL_B5WM)
Comments Population: Caucasian.
Characteristics: Has been designed to assay potential agonists/antagonists against ADCYAP1R1, modulating its activation and the following redistribution process inside the cells (Innoprot=P30214).
Characteristics: Transfected with ADCYAP1R1 N-terminally tagged with turboGFP.
Genetic integration: Method=Transfection/transduction; Gene=HGNC; HGNC:242; ADCYAP1R1.
Genetic integration: Method=Transfection/transduction; Gene=FPbase; A315M; TurboGFP (Note=Green fluorescent protein from P.plumata).
Derived from site: In situ; Bone, tibia; UBERON=UBERON_0000979.
Sequence variations
  • Mutation; HGNC; HGNC:9277; PPM1D; Simple; p.Arg458Ter (c.1372C>T); ClinVar=VCV002445214; Zygosity=Heterozygous (from parent cell line).
Disease Osteosarcoma (NCIt: C9145)
Osteosarcoma (ORDO: Orphanet_668)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0042 (U2OS)
Sex of cell Female
Age at sampling 15Y
Category Cancer cell line
Cross-references
Cell line collections (Providers) Innoprot; P30214
Encyclopedic resources Wikidata; Q112041875
Entry history
Entry creation17-Mar-2022
Last entry update19-Dec-2024
Version number8