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Cellosaurus SK-DSRCT1 (CVCL_B5EF)

[Text version]
Cell line name SK-DSRCT1
Synonyms SK-DSRCT-1
Accession CVCL_B5EF
Resource Identification Initiative To cite this cell line use: SK-DSRCT1 (RRID:CVCL_B5EF)
Comments Doubling time: 23.4 hours (PubMed=34841430).
Derived from site: In situ; Ascites; UBERON=UBERON_0007795.
Sequence variations
  • Gene fusion; HGNC; HGNC:3508; EWSR1 + HGNC; HGNC:12796; WT1; Name(s)=EWSR1-WT1, EWS-WT1; Note=EWSR1 Ex10-WT1 Ex8 fusion (PubMed=34841430).
  • Mutation; HGNC; HGNC:11110; ARID1A; Simple; p.Met1634Ter (c.4899delC); Zygosity=Unspecified (PubMed=34841430).
Disease Adult desmoplastic small round cell tumor (NCIt: C27373)
Desmoplastic small round cell tumor (ORDO: Orphanet_83469)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 21Y
Category Cancer cell line
Publications

PubMed=34841430; DOI=10.1242/dmm.047621; PMCID=PMC8807576
Smith R.S., Odintsov I., Liu Z.-B., Lui A.J.-W., Hayashi T., Vojnic M., Suehara Y., Delasos L., Mattar M.S., Hmeljak J., Ramirez H.A., Shaw M., Bui G., Hartono A.B., Gladstone E., Kunte S., Magnan H., Khodos I., de Stanchina E., La Quaglia M.P., Yao J.-J., Lae M., Lee S.B., Spraggon L., Pratilas C.A., Ladanyi M., Somwar R.
Novel patient-derived models of desmoplastic small round cell tumor enable validation of ERBB signaling as a potential therapeutic vulnerability.
Dis. Model. Mech. 15:dmm047621.1-dmm047621.15(2022)

Cross-references
Encyclopedic resources Wikidata; Q110433229
Entry history
Entry creation16-Dec-2021
Last entry update19-Dec-2024
Version number6