ID   SK-DSRCT1
AC   CVCL_B5EF
SY   SK-DSRCT-1
DR   Wikidata; Q110433229
RX   PubMed=34841430;
CC   Doubling time: 23.4 hours (PubMed=34841430).
CC   Sequence variation: Gene fusion; HGNC; HGNC:3508; EWSR1 + HGNC; HGNC:12796; WT1; Name(s)=EWSR1-WT1, EWS-WT1; Note=EWSR1 Ex10-WT1 Ex8 fusion (PubMed=34841430).
CC   Sequence variation: Mutation; HGNC; HGNC:11110; ARID1A; Simple; p.Met1634Ter (c.4899delC); Zygosity=Unspecified (PubMed=34841430).
CC   Derived from site: In situ; Ascites; UBERON=UBERON_0007795.
DI   NCIt; C27373; Adult desmoplastic small round cell tumor
DI   ORDO; Orphanet_83469; Desmoplastic small round cell tumor
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Female
AG   21Y
CA   Cancer cell line
DT   Created: 16-12-21; Last updated: 19-12-24; Version: 6
//
RX   PubMed=34841430; DOI=10.1242/dmm.047621; PMCID=PMC8807576;
RA   Smith R.S., Odintsov I., Liu Z.-B., Lui A.J.-W., Hayashi T., Vojnic M.,
RA   Suehara Y., Delasos L., Mattar M.S., Hmeljak J., Ramirez H.A.,
RA   Shaw M., Bui G., Hartono A.B., Gladstone E., Kunte S., Magnan H.,
RA   Khodos I., de Stanchina E., La Quaglia M.P., Yao J.-J., Lae M.,
RA   Lee S.B., Spraggon L., Pratilas C.A., Ladanyi M., Somwar R.;
RT   "Novel patient-derived models of desmoplastic small round cell tumor
RT   enable validation of ERBB signaling as a potential therapeutic
RT   vulnerability.";
RL   Dis. Model. Mech. 15:dmm047621.1-dmm047621.15(2022).
//