Cellosaurus cell line REX (CVCL

Cross-references
Cell line name	REX
Accession	CVCL_B501
Resource Identification Initiative	To cite this cell line use: REX (RRID:CVCL_B501)
Sequence variations	Mutation; HGNC; HGNC:7881; NOTCH1; Simple; p.Thr2466Met (c.7397C>T); ClinVar=VCV000241169; Zygosity=Heterozygous (PubMed=15472075).
Disease	T acute lymphoblastic leukemia (NCIt: C3183) Precursor T-cell acute lymphoblastic leukemia (ORDO: Orphanet_99861)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell	Sex unspecified
Age at sampling	Age unspecified
Category	Cancer cell line
Publications	PubMed=3100614; DOI=10.4049/jimmunol.138.3.726 Breitmeyer J.B., Oppenheim S.O., Daley J.F., Levine H.B., Schlossman S.F. Growth inhibition of human T cells by antibodies recognizing the T cell antigen receptor complex. J. Immunol. 138:726-731(1987) PubMed=15472075; DOI=10.1126/science.1102160 Weng A.P., Ferrando A.A., Lee W., Morris J.P. 4th, Silverman L.B., Sanchez-Irizarry C., Blacklow S.C., Look A.T., Aster J.C. Activating mutations of NOTCH1 in human T cell acute lymphoblastic leukemia. Science 306:269-271(2004)
Cell line databases/resources	cancercelllines; CVCL_B501
Encyclopedic resources	Wikidata; Q54949798
Polymorphism and mutation databases	Cosmic; 913421 Cosmic; 1524816
Entry history
Entry creation	06-Jun-2012
Last entry update	19-Dec-2024
Version number	11