ID   REX
AC   CVCL_B501
DR   cancercelllines; CVCL_B501
DR   Cosmic; 913421
DR   Cosmic; 1524816
DR   Wikidata; Q54949798
RX   PubMed=3100614;
RX   PubMed=15472075;
CC   Sequence variation: Mutation; HGNC; HGNC:7881; NOTCH1; Simple; p.Thr2466Met (c.7397C>T); ClinVar=VCV000241169; Zygosity=Heterozygous (PubMed=15472075).
DI   NCIt; C3183; T acute lymphoblastic leukemia
DI   ORDO; Orphanet_99861; Precursor T-cell acute lymphoblastic leukemia
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Sex unspecified
AG   Age unspecified
CA   Cancer cell line
DT   Created: 06-06-12; Last updated: 19-12-24; Version: 11
//
RX   PubMed=3100614; DOI=10.4049/jimmunol.138.3.726;
RA   Breitmeyer J.B., Oppenheim S.O., Daley J.F., Levine H.B.,
RA   Schlossman S.F.;
RT   "Growth inhibition of human T cells by antibodies recognizing the T
RT   cell antigen receptor complex.";
RL   J. Immunol. 138:726-731(1987).
//
RX   PubMed=15472075; DOI=10.1126/science.1102160;
RA   Weng A.P., Ferrando A.A., Lee W., Morris J.P. 4th, Silverman L.B.,
RA   Sanchez-Irizarry C., Blacklow S.C., Look A.T., Aster J.C.;
RT   "Activating mutations of NOTCH1 in human T cell acute lymphoblastic
RT   leukemia.";
RL   Science 306:269-271(2004).
//