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Cellosaurus NIZEDSM1iT21-C5 (CVCL_B4ZT)

[Text version]
Cell line name NIZEDSM1iT21-C5
Synonyms T21C5
Accession CVCL_B4ZT
Resource Identification Initiative To cite this cell line use: NIZEDSM1iT21-C5 (RRID:CVCL_B4ZT)
Comments Karyotypic information: Trisomic Chr21 cell line that originate from a mosaic Down syndrome individual.
Derived from site: In situ; Skin; UBERON=UBERON_0002097.
Cell type: Fibroblast of skin; CL=CL_0002620.
Disease Down syndrome (NCIt: C2993)
Down syndrome (ORDO: Orphanet_870)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_B4ZP (CM05287)
Age at sampling Adult
Category Induced pluripotent stem cell
Publications

PubMed=25694335; DOI=10.1002/stem.1968; PMCID=PMC4737213
Murray A., Letourneau A., Canzonetta C., Stathaki E., Gimelli S., Sloan-Bena F., Abrehart R., Goh P., Lim S., Baldo C., Dagna-Bricarelli F., Hannan S., Mortensen M., Ballard D., Syndercombe-Court D., Fusaki N., Hasegawa M., Smart T.G., Bishop C., Antonarakis S.E., Groet J., Nizetic D.
Brief report: isogenic induced pluripotent stem cell lines from an adult with mosaic Down syndrome model accelerated neuronal ageing and neurodegeneration.
Stem Cells 33:2077-2084(2015)

Cross-references
Encyclopedic resources Wikidata; Q110433102
Entry history
Entry creation16-Dec-2021
Last entry update29-Jun-2023
Version number4