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Cellosaurus Hair-M (CVCL_B401)

[Text version]
Cell line name Hair-M
Synonyms HAIR-M; Hair M
Accession CVCL_B401
Resource Identification Initiative To cite this cell line use: Hair-M (RRID:CVCL_B401)
Comments Problematic cell line: Possibly misclassified. It is not certain that this cell line originate from a hairy cell leukemia (PubMed=22653958).
Part of: LL-100 blood cancer cell line panel.
Population: Japanese.
Doubling time: 48 hours (PubMed=2418246); ~48 hours (DSMZ=ACC-762).
Omics: Deep exome analysis.
Omics: Transcriptome analysis by RNAseq.
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Sequence variations
  • Gene fusion; HGNC; 5477; IGH + HGNC; 11648; TCL1A; Name(s)=IGH-TCL1A (PubMed=31160637).
HLA typing Source: DSMZCellDive=ACC-762
Class I
HLA-AA*24:02:01,26:02:01
HLA-BB*40:06:01,48:01:01
HLA-CC*08:01:01,08:01:01
Class II
HLA-DPDPA1*02:02:02,02:02:02
DPB1*05:01:01,05:01:01
HLA-DQDQA1*01:03:01,01:04:01
DQB1*05:03:01,06:01:01
HLA-DRDRA*01:01:01,01:02:02
DRB1*08:03:02,14:05:01
Disease Hairy cell leukemia (NCIt: C7402)
Classic hairy cell leukemia (ORDO: Orphanet_58017)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 86Y
Category Cancer cell line
STR profile Source(s): DSMZ=ACC-762

Markers:
AmelogeninX,Y
CSF1PO10,13
D2S133817,24
D3S135815
D5S81811,13
D7S82012
D8S117911,15
D13S3179,10
D16S5399,11
D18S5114,17
D19S43314,16
D21S1130
FGA21,24
Penta D9,11
Penta E10,15
TH016
TPOX9,11
vWA16,17

Run an STR similarity search on this cell line
Publications

PubMed=6608852
Matsuo Y., Sagawa K., Yokoyama M., Koga T., Yamaguchi T., Morita M., Minowada J.
Establishment and characterization of hairy cell leukemia cell line (Hair-M).
Nihon Ketsueki Gakkai Zasshi 46:1222-1232(1983)

PubMed=2418246; DOI=10.1093/jnci/76.2.207
Matsuo Y., Sagawa K., Morita M., Minowada J., Yokoyama M.M.
Establishment of a hairy cell leukemia cell line carrying Tac antigen and phagocytic activity with B-cell characteristics.
J. Natl. Cancer Inst. 76:207-216(1986)

PubMed=11060441; DOI=10.1159/000015656
Lindbjerg Andersen C., Ostergaard M.V., Nielsen B., Pedersen B., Koch J.
Characterization of three hairy cell leukemia- derived cell lines (ESKOL, JOK-1, and Hair-M) by multiplex-FISH, comparative genomic hybridization, FISH, PRINS, and dideoxyPRINS.
Cytogenet. Cell Genet. 90:30-39(2000)

DOI=10.1016/B978-0-12-221970-2.50457-5
Drexler H.G.
The leukemia-lymphoma cell line factsbook.
(In book) ISBN 9780122219702; pp.1-733; Academic Press; London; United Kingdom (2001)

PubMed=22653958; DOI=10.1182/blood-2011-12-400374
Tiacci E., Pucciarini A., Bigerna B., Pettirossi V., Strozzini F., Martelli M.P., Tabarrini A., Drexler H.G., Falini B.
Absence of BRAF-V600E in the human cell lines BONNA-12, ESKOL, HAIR-M, and HC-1 questions their origin from hairy cell leukemia.
Blood 119:5332-5333(2012)

PubMed=31160637; DOI=10.1038/s41598-019-44491-x; PMCID=PMC6547646
Quentmeier H., Pommerenke C., Dirks W.G., Eberth S., Koeppel M., MacLeod R.A.F., Nagel S., Steube K.G., Uphoff C.C., Drexler H.G.
The LL-100 panel: 100 cell lines for blood cancer studies.
Sci. Rep. 9:8218-8218(2019)

Cross-references
Cell line collections (Providers) DSMZ; ACC-762
Cell line databases/resources DSMZCellDive; ACC-762
Encyclopedic resources Wikidata; Q54872376
Gene expression databases ArrayExpress; E-MTAB-7721
ArrayExpress; E-MTAB-7722
Polymorphism and mutation databases Cosmic; 999764
Cosmic; 1809511
Cosmic; 2690008
Entry history
Entry creation06-Jun-2012
Last entry update02-May-2024
Version number20