ID   Hair-M
AC   CVCL_B401
SY   HAIR-M; Hair M
DR   ArrayExpress; E-MTAB-7721
DR   ArrayExpress; E-MTAB-7722
DR   Cosmic; 999764
DR   Cosmic; 1809511
DR   Cosmic; 2690008
DR   DSMZ; ACC-762
DR   DSMZCellDive; ACC-762
DR   Wikidata; Q54872376
RX   DOI=10.1016/B978-0-12-221970-2.50457-5;
RX   PubMed=2418246;
RX   PubMed=6608852;
RX   PubMed=11060441;
RX   PubMed=22653958;
RX   PubMed=31160637;
CC   Problematic cell line: Possibly misclassified. It is not certain that this cell line originate from a hairy cell leukemia (PubMed=22653958).
CC   Part of: LL-100 blood cancer cell line panel.
CC   Population: Japanese.
CC   Doubling time: 48 hours (PubMed=2418246); ~48 hours (DSMZ=ACC-762).
CC   HLA typing: A*24:02:01,26:02:01; B*40:06:01,48:01:01; C*08:01:01,08:01:01; DPA1*02:02:02,02:02:02; DPB1*05:01:01,05:01:01; DQA1*01:03:01,01:04:01; DQB1*05:03:01,06:01:01; DRA*01:01:01,01:02:02; DRB1*08:03:02,14:05:01 (DSMZCellDive=ACC-762).
CC   Sequence variation: Gene fusion; HGNC; 5477; IGH + HGNC; 11648; TCL1A; Name(s)=IGH-TCL1A (PubMed=31160637).
CC   Omics: Deep exome analysis.
CC   Omics: Transcriptome analysis by RNAseq.
CC   Derived from sampling site: Peripheral blood.
ST   Source(s): DSMZ
ST   Amelogenin: X,Y
ST   CSF1PO: 10,13
ST   D13S317: 9,10
ST   D16S539: 9,11
ST   D18S51: 14,17
ST   D19S433: 14,16
ST   D21S11: 30
ST   D2S1338: 17,24
ST   D3S1358: 15
ST   D5S818: 11,13
ST   D7S820: 12
ST   D8S1179: 11,15
ST   FGA: 21,24
ST   Penta D: 9,11
ST   Penta E: 10,15
ST   TH01: 6
ST   TPOX: 9,11
ST   vWA: 16,17
DI   NCIt; C7402; Hairy cell leukemia
DI   ORDO; Orphanet_58017; Classic hairy cell leukemia
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
AG   86Y
CA   Cancer cell line
DT   Created: 06-06-12; Last updated: 21-03-23; Version: 18
RX   DOI=10.1016/B978-0-12-221970-2.50457-5;
RA   Drexler H.G.;
RT   "The leukemia-lymphoma cell line factsbook.";
RL   (In) ISBN 9780122219702; pp.1-733; Academic Press; London (2001).
RX   PubMed=2418246; DOI=10.1093/jnci/76.2.207;
RA   Matsuo Y., Sagawa K., Morita M., Minowada J., Yokoyama M.M.;
RT   "Establishment of a hairy cell leukemia cell line carrying Tac antigen
RT   and phagocytic activity with B-cell characteristics.";
RL   J. Natl. Cancer Inst. 76:207-216(1986).
RX   PubMed=6608852;
RA   Matsuo Y., Sagawa K., Yokoyama M., Koga T., Yamaguchi T., Morita M.,
RA   Minowada J.;
RT   "Establishment and characterization of hairy cell leukemia cell line
RT   (Hair-M).";
RL   Nihon Ketsueki Gakkai Zasshi 46:1222-1232(1983).
RX   PubMed=11060441; DOI=10.1159/000015656;
RA   Lindbjerg Andersen C., Ostergaard M., Nielsen B., Pedersen B.,
RA   Koch J.;
RT   "Characterization of three hairy cell leukemia- derived cell lines
RT   (ESKOL, JOK-1, and Hair-M) by multiplex-FISH, comparative genomic
RT   hybridization, FISH, PRINS, and dideoxyPRINS.";
RL   Cytogenet. Cell Genet. 90:30-39(2000).
RX   PubMed=22653958; DOI=10.1182/blood-2011-12-400374;
RA   Tiacci E., Pucciarini A., Bigerna B., Pettirossi V., Strozzini F.,
RA   Martelli M.P., Tabarrini A., Drexler H.G., Falini B.;
RT   "Absence of BRAF-V600E in the human cell lines BONNA-12, ESKOL, HAIR-M,
RT   and HC-1 questions their origin from hairy cell leukemia.";
RL   Blood 119:5332-5333(2012).
RX   PubMed=31160637; DOI=10.1038/s41598-019-44491-x;
RA   Quentmeier H., Pommerenke C., Dirks W.G., Eberth S., Koeppel M.,
RA   MacLeod R.A.F., Nagel S., Steube K., Uphoff C.C., Drexler H.G.;
RT   "The LL-100 panel: 100 cell lines for blood cancer studies.";
RL   Sci. Rep. 9:8218-8218(2019).