Cellosaurus logo
expasy logo

Cellosaurus HUES 8 (CVCL_B207)

[Text version]
Cell line name HUES 8
Synonyms HUES-8; HUES8; HuES8; HVRDe008-A
Accession CVCL_B207
Resource Identification Initiative To cite this cell line use: HUES 8 (RRID:CVCL_B207)
Comments From: Harvard University; Boston; USA.
Registration: NIH Human Embryonic Stem Cell Registry; NIHhESC-10-0021.
Registration: Swiss research registry; BAG-hES-IMP-0056.
Registration: UK Stem Cell Bank (UKSCB); R-06-018, Steering comm. appl. SCSC04-25(8).
Doubling time: 48 hours (PubMed=14999088).
Omics: DNA methylation analysis.
Omics: Transcriptome analysis by microarray.
Derived from site: In situ; Blastocyst; UBERON=UBERON_0000358.
Cell type: Embryonic stem cell; CL=CL_0002322.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_VR10 (HUES8 iCas9)CVCL_A8ZA (HVRDe008-A-1)CVCL_B5S4 (HVRDe008-A-2)
Sex of cell Male
Age at sampling Blastocyst stage
Category Embryonic stem cell
STR profile Source(s): PubMed=19200798; PubMed=21637780

Markers:
AmelogeninX,Y
CSF1PO10,12
D3S135815,19
D5S81811
D7S82011,12
D8S117913
D13S31712,14
D16S5399,12
D18S5112,16
D21S1128,29
FGA20,25
Penta D10,11
Penta E7,10
TH017,9
TPOX8,11
vWA15,19

Run an STR similarity search on this cell line
Publications

PubMed=14999088; DOI=10.1056/NEJMsr040330
Cowan C.A., Klimanskaya I.V., McMahon J., Atienza J., Witmyer J., Zucker J.P., Wang S.-P., Morton C.C., McMahon A.P., Powers D., Melton D.A.
Derivation of embryonic stem-cell lines from human blastocysts.
N. Engl. J. Med. 350:1353-1356(2004)

PubMed=17572666; DOI=10.1038/nbt1318
Adewumi O., Aflatoonian B., Ahrlund-Richter L., Amit M., Andrews P.W., Beighton G., Bello P.A., Benvenisty N., Berry L.S., Bevan S., Blum B., Brooking J., Chen K.G., Choo A.B.-H., Churchill G.A., Corbel M., Damjanov I., Draper J.S., Dvorak P., Emanuelsson K., Fleck R.A., Ford A., Gertow K., Gertsenstein M., Gokhale P.J., Hamilton R.S., Hampl A., Healy L.E., Hovatta O., Hyllner J., Imreh M.P., Itskovitz-Eldor J., Jackson J., Johnson J.L., Jones M., Kee K., King B.L., Knowles B.B., Lako M., Lebrin F., Mallon B.S., Manning D., Mayshar Y., McKay R.D.G., Michalska A.E., Mikkola M., Mileikovsky M., Minger S.L., Moore H.D., Mummery C.L., Nagy A., Nakatsuji N., O'Brien C.M., Oh S.K.-W., Olsson C., Otonkoski T., Park K.-Y., Passier R., Patel H., Patel M.J., Pedersen R., Pera M.F., Piekarczyk M.S., Reijo Pera R.A., Reubinoff B.E., Robins A.J., Rossant J., Rugg-Gunn P., Schulz T.C., Semb H., Sherrer E.S., Siemen H., Stacey G.N., Stojkovic M., Suemori H., Szatkiewicz J., Turetsky T.T., Tuuri T., van den Brink S., Vintersten K., Vuoristo S., Ward-van Oostwaard D., Weaver T.A., Young L.A., Zhang W.-D.
International Stem Cell Initiative
Characterization of human embryonic stem cell lines by the International Stem Cell Initiative.
Nat. Biotechnol. 25:803-816(2007)

PubMed=19200798; DOI=10.1016/j.stem.2008.12.001; PMCID=PMC3335201
Chen A.E., Egli D.M., Niakan K.K., Deng J., Akutsu H., Yamaki M., Cowan C.A., Fitz-Gerald C., Zhang K., Melton D.A., Eggan K.C.
Optimal timing of inner cell mass isolation increases the efficiency of human embryonic stem cell derivation and allows generation of sibling cell lines.
Cell Stem Cell 4:103-106(2009)

PubMed=21295703; DOI=10.1016/j.cell.2010.12.032; PMCID=PMC3063454
Bock C., Kiskinis E., Verstappen G., Gu H.-C., Boulting G.L., Smith Z.D., Ziller M.J., Croft G.F., Amoroso M.W., Oakley D.H., Gnirke A., Eggan K.C., Meissner A.
Reference maps of human ES and iPS cell variation enable high-throughput characterization of pluripotent cell lines.
Cell 144:439-452(2011)

PubMed=21637780; DOI=10.1371/journal.pgen.1002085; PMCID=PMC3102737
Nishino K., Toyoda M., Yamazaki-Inoue M., Fukawatase Y., Chikazawa E., Sakaguchi H., Akutsu H., Umezawa A.
DNA methylation dynamics in human induced pluripotent stem cells over time.
PLoS Genet. 7:E1002085-E1002085(2011)

Cross-references
Cell line databases/resources hPSCreg; HVRDe008-A
NIHhESC; NIHhESC-10-0021
SKIP; SKIP001912
Biological sample resources ENCODE; ENCBS458EUG
ENCODE; ENCBS989VLH
Encyclopedic resources Wikidata; Q54896820
Experimental variables resources EFO; EFO_0007093
Gene expression databases GEO; GSM608013
GEO; GSM608030
GEO; GSM621709
GEO; GSM637761
Entry history
Entry creation06-Jun-2012
Last entry update10-Sep-2024
Version number23