Cellosaurus cell line Abcam SW480 SERPINA1 KO (CVCL

Cross-references
Cell line name	Abcam SW480 SERPINA1 KO
Synonyms	Human SERPINA1 knockout SW480
Accession	CVCL_B0YW
Resource Identification Initiative	To cite this cell line use: Abcam SW480 SERPINA1 KO (RRID:CVCL_B0YW)
Comments	Population: Caucasian. Knockout cell: Method=CRISPR/Cas9; HGNC; HGNC:8941; SERPINA1. Derived from site: In situ; Colon; UBERON=UBERON_0001155.
Sequence variations	Mutation; HGNC; HGNC:583; APC; Simple; p.Gln1338Ter (c.4012C>T); ClinVar=VCV000000801; Zygosity=Homozygous (from parent cell line). Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Gly12Val (c.35G>T); ClinVar=VCV000012583; Zygosity=Homozygous (from parent cell line). Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg273His (c.818G>A); ClinVar=VCV000012366; Zygosity=Heterozygous (from parent cell line). Mutation; HGNC; HGNC:11998; TP53; Simple; p.Pro309Ser (c.925C>T); ClinVar=VCV000458575; Zygosity=Heterozygous (from parent cell line).
Disease	Colon adenocarcinoma (NCIt: C4349)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy	Parent: CVCL_0546 (SW480)
Sex of cell	Male
Age at sampling	51Y
Category	Cancer cell line
Cell line collections (Providers)	Abcam; ab270488
Cell line databases/resources	cancercelllines; CVCL_B0YW
Encyclopedic resources	Wikidata; Q110432534
Entry history
Entry creation	16-Dec-2021
Last entry update	19-Dec-2024
Version number	6