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Cellosaurus Abcam SW480 LCN2 KO (CVCL_B0YV)

[Text version]
Cell line name Abcam SW480 LCN2 KO
Synonyms Human LCN2 knockout SW480
Accession CVCL_B0YV
Resource Identification Initiative To cite this cell line use: Abcam SW480 LCN2 KO (RRID:CVCL_B0YV)
Comments Population: Caucasian.
Knockout cell: Method=CRISPR/Cas9; HGNC; 6526; LCN2.
Derived from site: In situ; Colon; UBERON=UBERON_0001155.
Sequence variations
  • Mutation; HGNC; 583; APC; Simple; p.Gln1338Ter (c.4012C>T); ClinVar=VCV000000801; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; 6407; KRAS; Simple; p.Gly12Val (c.35G>T); ClinVar=VCV000012583; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; 11998; TP53; Simple; p.Arg273His (c.818G>A); ClinVar=VCV000012366; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; 11998; TP53; Simple; p.Pro309Ser (c.925C>T); ClinVar=VCV000458575; Zygosity=Heterozygous (from parent cell line).
Disease Colon adenocarcinoma (NCIt: C4349)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0546 (SW480)
Sex of cell Male
Age at sampling 51Y
Category Cancer cell line
Cross-references
Cell line collections (Providers) Abcam; ab270486
Cell line databases/resources cancercelllines; CVCL_B0YV
Encyclopedic resources Wikidata; Q110432533
Entry history
Entry creation16-Dec-2021
Last entry update05-Oct-2023
Version number5