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Cellosaurus NIKS-16deltaE7 (CVCL_B0UN)

[Text version]
Cell line name NIKS-16deltaE7
Synonyms BC-1-Ep/SL/HPV-16/E7TTL; 13-9
Accession CVCL_B0UN
Resource Identification Initiative To cite this cell line use: NIKS-16deltaE7 (RRID:CVCL_B0UN)
Comments Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P00552; Transposon Tn5 neo.
Transformant: NCBI_TaxID; 333760; Human papillomavirus type 16 (HPV16) (Note=With defective E7).
Omics: Transcriptome analysis by microarray.
Derived from site: In situ; Foreskin, skin, epidermis; UBERON=UBERON_0001471+UBERON_0001003.
Cell type: Keratinocyte; CL=CL_0000312.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_A1LW (NIKS)
Sex of cell Male
Age at sampling <1M
Category Transformed cell line
Publications

PubMed=10864676; DOI=10.1128/JVI.74.14.6622-6631.2000; PMCID=PMC112172
Flores E.R., Allen-Hoffmann B.L., Lee D.L., Lambert P.F.
The human papillomavirus type 16 E7 oncogene is required for the productive stage of the viral life cycle.
J. Virol. 74:6622-6631(2000)

PubMed=28623356; DOI=10.1038/s41598-017-03295-7; PMCID=PMC5473897
Cicchini L., Blumhagen R.Z., Westrich J.A., Myers M.E., Warren C.J., Siska C., Raben D., Kechris K.J., Pyeon D.
High-risk human papillomavirus E7 alters host DNA methylome and represses HLA-E expression in human keratinocytes.
Sci. Rep. 7:3633-3633(2017)

Cross-references
Encyclopedic resources Wikidata; Q108821046
Gene expression databases GEO; GSM2197781
GEO; GSM2197782
GEO; GSM2197783
Entry history
Entry creation23-Sep-2021
Last entry update10-Sep-2024
Version number6