Cellosaurus cell line ID1-V-LUC hES (CVCL

Cellosaurus ID1-V-LUC hES (CVCL_B0JB)

Cross-references
Cell line name	ID1-V-LUC hES
Synonyms	CGMCC11091
Accession	CVCL_B0JB
Resource Identification Initiative	To cite this cell line use: ID1-V-LUC hES (RRID:CVCL_B0JB)
Comments	Group: Patented cell line. Registration: International Depositary Authority, China General Microbiological Culture Collection Center; CGMCC No.11091. Characteristics: Stem cell model for screening drugs for pulmonary hypertension and to find a novel lead compound for the treatment of pulmonary hypertension using BMP signaling. Characteristics: Transduced with a Id1-Venus-Luc-MC1-DTA construct in which expression of the genes for Venus and luciferase are under the control of a full-length human ID1 promoter. Genetic integration: Method=Transduction; Gene=FPbase; YUJWJ; Venus (Note=Bright yellow fluorescent protein derived from GFP). Genetic integration: Method=Transduction; Gene=UniProtKB; P08659; Firefly luciferase. Derived from site: In situ; Blastocyst; UBERON=UBERON_0000358. Cell type: Embryonic stem cell; CL=CL_0002322.
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy	Parent: CVCL_9773 (WA09)
Sex of cell	Female
Age at sampling	Blastocyst stage
Category	Embryonic stem cell
Publications	Patent=US20180172669 Yang Y., Zhou F., Gong S.-Q., Wei Q.-X., Zhao S., Si S.-Y. Screening and use of piperidino pyrazolopyrimidine compound. Patent number US20180172669, 21-Jun-2018 PubMed=29449428; DOI=10.1183/13993003.02229-2017 Xing Y.-Z., Zhao S., Wei Q.-X., Gong S.-Q., Zhao X., Zhou F., Al-Lamki R., Ortmann D., Du M.-X., Pedersen R., Shang G.-D., Si S.-Y., Morrell N.W., Yang J. A novel piperidine identified by stem cell-based screening attenuates pulmonary arterial hypertension by regulating BMP2 and PTGS2 levels. Eur. Respir. J. 51:1702229-1702229(2018)
Encyclopedic resources	Wikidata; Q108820530
Entry history
Entry creation	23-Sep-2021
Last entry update	10-Sep-2024
Version number	7