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Cellosaurus F98npEGFRvIII (CVCL_B048)

[Text version]
Cell line name F98npEGFRvIII
Accession CVCL_B048
Resource Identification Initiative To cite this cell line use: F98npEGFRvIII (RRID:CVCL_B048)
Comments Doubling time: ~17 hours (ATCC=CRL-2949).
Genetic integration: Method=Transfection/transduction; Gene=HGNC; HGNC:3236; EGFR (Note=With p.Val30_Arg297del = EGFRvIII).
Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P00552; Transposon Tn5 neo.
Transformant: ChEBI; CHEBI_23995; N-ethyl-N-nitrosourea (ENU).
Derived from site: In situ; Brain, cerebellum; UBERON=UBERON_0002037.
Disease Rat malignant glioma (NCIt: C64069)
Species of origin Rattus norvegicus (Rat) (NCBI Taxonomy: 10116)
Breed/subspecies: Fischer 344; RS=RS:0000215.
Hierarchy Parent: CVCL_3510 (F98)
Sex of cell Female
Age at sampling 20FD
Category Cancer cell line
Publications

PubMed=15671565; DOI=10.1158/1078-0432.341.11.1
Yang W.-L., Barth R.F., Wu G., Ciesielski M.J., Fenstermaker R.A., Moffat B.A., Ross B.D., Wikstrand C.J.
Development of a syngeneic rat brain tumor model expressing EGFRvIII and its use for molecular targeting studies with monoclonal antibody L8A4.
Clin. Cancer Res. 11:341-350(2005)

Cross-references
Cell line collections (Providers) ATCC; CRL-2949
Encyclopedic resources Wikidata; Q54833168
Entry history
Entry creation06-Jun-2012
Last entry update19-Dec-2024
Version number13