ID   F98npEGFRvIII
AC   CVCL_B048
DR   ATCC; CRL-2949
DR   Wikidata; Q54833168
RX   PubMed=15671565;
CC   Doubling time: ~17 hours (ATCC=CRL-2949).
CC   Genetic integration: Method=Transfection/transduction; Gene=HGNC; HGNC:3236; EGFR (Note=With p.Val30_Arg297del = EGFRvIII).
CC   Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P00552; Transposon Tn5 neo.
CC   Transformant: ChEBI; CHEBI_23995; N-ethyl-N-nitrosourea (ENU).
CC   Derived from site: In situ; Brain, cerebellum; UBERON=UBERON_0002037.
CC   Breed/subspecies: Fischer 344; RS=RS:0000215.
DI   NCIt; C64069; Rat malignant glioma
OX   NCBI_TaxID=10116; ! Rattus norvegicus (Rat)
HI   CVCL_3510 ! F98
SX   Female
AG   20FD
CA   Cancer cell line
DT   Created: 06-06-12; Last updated: 19-12-24; Version: 13
//
RX   PubMed=15671565; DOI=10.1158/1078-0432.341.11.1;
RA   Yang W.-L., Barth R.F., Wu G., Ciesielski M.J., Fenstermaker R.A.,
RA   Moffat B.A., Ross B.D., Wikstrand C.J.;
RT   "Development of a syngeneic rat brain tumor model expressing EGFRvIII
RT   and its use for molecular targeting studies with monoclonal antibody
RT   L8A4.";
RL   Clin. Cancer Res. 11:341-350(2005).
//