Cellosaurus cell line SW480/5FUR (CVCL

Cross-references
Cell line name	SW480/5FUR
Accession	CVCL_AU16
Resource Identification Initiative	To cite this cell line use: SW480/5FUR (RRID:CVCL_AU16)
Comments	Population: Caucasian. Selected for resistance to: ChEBI; CHEBI_46345; 5-fluorouracil (5-FU). Derived from site: In situ; Colon; UBERON=UBERON_0001155.
Sequence variations	Mutation; HGNC; HGNC:583; APC; Simple; p.Gln1338Ter (c.4012C>T); ClinVar=VCV000000801; Zygosity=Homozygous (from parent cell line). Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Gly12Val (c.35G>T); ClinVar=VCV000012583; Zygosity=Homozygous (from parent cell line). Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg273His (c.818G>A); ClinVar=VCV000012366; Zygosity=Heterozygous (from parent cell line). Mutation; HGNC; HGNC:11998; TP53; Simple; p.Pro309Ser (c.925C>T); ClinVar=VCV000458575; Zygosity=Heterozygous (from parent cell line).
Disease	Colon adenocarcinoma (NCIt: C4349)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy	Parent: CVCL_0546 (SW480)
Sex of cell	Male
Age at sampling	51Y
Category	Cancer cell line
Web pages	https://www.mdanderson.org/education-and-research/resources-for-professionals/scientific-resources/core-facilities-and-services/characterized-cell-line-core-facility/services/cclc-list-to-distribute-updated.xlsx
Cell line databases/resources	cancercelllines; CVCL_AU16
Encyclopedic resources	Wikidata; Q54971156
Entry history
Entry creation	02-May-2016
Last entry update	19-Dec-2024
Version number	15