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Cellosaurus HTh74 clone 7 (CVCL_AT82)

[Text version]
Cell line name HTh74 clone 7
Synonyms HTh-74 clone7; U-Hth74-clone7
Accession CVCL_AT82
Resource Identification Initiative To cite this cell line use: HTh74 clone 7 (RRID:CVCL_AT82)
Comments Derived from site: In situ; Thyroid gland; UBERON=UBERON_0002046.
Cell type: Epithelial cell; CL=CL_0000066.
Sequence variations
  • Mutation; HGNC; HGNC:7765; NF1; Simple; p.Leu732fs (c.2195_2202delTGCCCAAC); Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Homozygous; Note=In promoter (from parent cell line).
Disease Thyroid gland anaplastic carcinoma (NCIt: C3878)
Anaplastic thyroid carcinoma (ORDO: Orphanet_142)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_6288 (HTh74)
Sex of cell Female
Age at sampling 73Y
Category Cancer cell line
STR profile Source(s): PubMed=21868764

Markers:
AmelogeninX
CSF1PO10,12
D5S81811,12
D7S8208,9
D13S31712,13
D16S53911
TH018,9
TPOX11
vWA17,19

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Publications

PubMed=21868764; DOI=10.1158/1078-0432.CCR-11-0690; PMCID=PMC3229662
Zhao M., Sano D., Pickering C.R., Jasser S.A., Henderson Y.C., Clayman G.L., Sturgis E.M., Ow T.J., Lotan R., Carey T.E., Sacks P.G., Grandis J.R., Sidransky D., Heldin N.-E., Myers J.N.
Assembly and initial characterization of a panel of 85 genomically validated cell lines from diverse head and neck tumor sites.
Clin. Cancer Res. 17:7248-7264(2011)

Cross-references
Encyclopedic resources Wikidata; Q54896657
Entry history
Entry creation02-May-2016
Last entry update19-Dec-2024
Version number13