ID   HTh74 clone 7
AC   CVCL_AT82
SY   HTh-74 clone7; U-Hth74-clone7
DR   Wikidata; Q54896657
RX   PubMed=21868764;
CC   Sequence variation: Mutation; HGNC; HGNC:7765; NF1; Simple; p.Leu732fs (c.2195_2202delTGCCCAAC); Zygosity=Homozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Homozygous; Note=In promoter (from parent cell line).
CC   Derived from site: In situ; Thyroid gland; UBERON=UBERON_0002046.
CC   Cell type: Epithelial cell; CL=CL_0000066.
ST   Source(s): PubMed=21868764
ST   Amelogenin: X
ST   CSF1PO: 10,12
ST   D13S317: 12,13
ST   D16S539: 11
ST   D5S818: 11,12
ST   D7S820: 8,9
ST   TH01: 8,9
ST   TPOX: 11
ST   vWA: 17,19
DI   NCIt; C3878; Thyroid gland anaplastic carcinoma
DI   ORDO; Orphanet_142; Anaplastic thyroid carcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_6288 ! HTh74
SX   Female
AG   73Y
CA   Cancer cell line
DT   Created: 02-05-16; Last updated: 19-12-24; Version: 13
//
RX   PubMed=21868764; DOI=10.1158/1078-0432.CCR-11-0690; PMCID=PMC3229662;
RA   Zhao M., Sano D., Pickering C.R., Jasser S.A., Henderson Y.C.,
RA   Clayman G.L., Sturgis E.M., Ow T.J., Lotan R., Carey T.E., Sacks P.G.,
RA   Grandis J.R., Sidransky D., Heldin N.-E., Myers J.N.;
RT   "Assembly and initial characterization of a panel of 85 genomically
RT   validated cell lines from diverse head and neck tumor sites.";
RL   Clin. Cancer Res. 17:7248-7264(2011).
//