Cell line name |
SW480R |
Synonyms |
SW480 R2 |
Accession |
CVCL_AT68 |
Resource Identification Initiative |
To cite this cell line use: SW480R (RRID:CVCL_AT68) |
Comments |
Population: Caucasian. Derived from site: In situ; Colon; UBERON=UBERON_0001155. |
Sequence variations |
- Mutation; HGNC; 583; APC; Simple; p.Gln1338Ter (c.4012C>T); ClinVar=VCV000000801; Zygosity=Homozygous (from parent cell line).
- Mutation; HGNC; 6407; KRAS; Simple; p.Gly12Val (c.35G>T); ClinVar=VCV000012583; Zygosity=Homozygous (from parent cell line).
- Mutation; HGNC; 11998; TP53; Simple; p.Arg273His (c.818G>A); ClinVar=VCV000012366; Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; 11998; TP53; Simple; p.Pro309Ser (c.925C>T); ClinVar=VCV000458575; Zygosity=Heterozygous (from parent cell line).
|
Disease |
Colon adenocarcinoma (NCIt: C4349) |
Species of origin |
Homo sapiens (Human)
(NCBI Taxonomy: 9606) |
Hierarchy |
Parent: CVCL_0546 (SW480) |
Sex of cell |
Male |
Age at sampling |
51Y |
Category |
Cancer cell line |
Publications | PubMed=1458472 Tomita N., Jiang W., Hibshoosh H., Warburton D., Kahn S.M., Weinstein I.B. Isolation and characterization of a highly malignant variant of the SW480 human colon cancer cell line. Cancer Res. 52:6840-6847(1992) Patent=US7989001 Kim U., Cohen S.A. Method of separating tumor cells with and without lymphotropic metastatic potential in a human carcinoma. Patent number US7989001, 02-Aug-2011 |
Cross-references |
Cell line databases/resources |
cancercelllines; CVCL_AT68
|
Encyclopedic resources |
Wikidata; Q54971174
|
Entry history |
Entry creation | 02-May-2016 |
Last entry update | 05-Oct-2023 |
Version number | 14 |
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