| Cell line name |
SW480R |
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| Synonyms |
SW480 R2 |
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| Accession |
CVCL_AT68 |
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| Resource Identification Initiative |
To cite this cell line use: SW480R (RRID:CVCL_AT68) |
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| Comments |
Population: Caucasian.
Derived from site: In situ; Colon; UBERON=UBERON_0001155. |
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| Sequence variations |
- Mutation; HGNC; HGNC:583; APC; Simple; p.Gln1338Ter (c.4012C>T); ClinVar=VCV000000801; Zygosity=Homozygous (from parent cell line).
- Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Gly12Val (c.35G>T); ClinVar=VCV000012583; Zygosity=Homozygous (from parent cell line).
- Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg273His (c.818G>A); ClinVar=VCV000012366; Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; HGNC:11998; TP53; Simple; p.Pro309Ser (c.925C>T); ClinVar=VCV000458575; Zygosity=Heterozygous (from parent cell line).
|
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| Disease |
Colon adenocarcinoma (NCIt: C4349) |
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| Species of origin |
Homo sapiens (Human)
(NCBI Taxonomy: 9606) |
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| Hierarchy |
Parent: CVCL_0546 (SW480) |
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| Sex of cell |
Male |
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| Age at sampling |
51Y |
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| Category |
Cancer cell line |
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| Publications | PubMed=1458472
Tomita N., Jiang W., Hibshoosh H., Warburton D., Kahn S.M., Weinstein I.B.
Isolation and characterization of a highly malignant variant of the SW480 human colon cancer cell line.
Cancer Res. 52:6840-6847(1992) Patent=US7989001
Kim U., Cohen S.A.
Method of separating tumor cells with and without lymphotropic metastatic potential in a human carcinoma.
Patent number US7989001, 02-Aug-2011 |
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| Cross-references |
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| Cell line databases/resources |
cancercelllines; CVCL_AT68
|
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| Encyclopedic resources |
Wikidata; Q54971174
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| Entry history |
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| Entry creation | 02-May-2016 |
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| Last entry update | 19-Dec-2024 |
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| Version number | 15 |
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