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Cellosaurus BDEneu (CVCL_AS29)

[Text version]
Cell line name BDEneu
Accession CVCL_AS29
Resource Identification Initiative To cite this cell line use: BDEneu (RRID:CVCL_AS29)
Comments Doubling time: ~17-19 hours (PubMed=18081149).
Genetic integration: Method=Transduction; Gene=RGD; 2561; Erbb2 (Note=With p.Val661Glu).
Genetic integration: Method=Transduction; Gene=UniProtKB; P00552; Transposon Tn5 neo.
Transformant: Activated Erbb2/neu.
Derived from site: In situ; Bile duct; UBERON=UBERON_0002394.
Cell type: Cholangiocyte; CL=CL_1000488.
Species of origin Rattus norvegicus (Rat) (NCBI Taxonomy: 10116)
Breed/subspecies: Fischer 344; RS=RS_0000215.
Hierarchy Parent: CVCL_AS28 (BDE1)
Sex of cell Male
Category Transformed cell line
Publications

PubMed=16344070; DOI=10.1053/j.gastro.2005.10.010
Lai G.-H., Zhang Z.-C., Shen X.-N., Ward D.J., DeWitt J.L., Holt S.E., Rozich R.A., Hixson D.C., Sirica A.E.
erbB-2/neu transformed rat cholangiocytes recapitulate key cellular and molecular features of human bile duct cancer.
Gastroenterology 129:2047-2057(2005)

PubMed=18081149; DOI=10.1002/hep.22088
Sirica A.E., Zhang Z.-C., Lai G.-H., Asano T., Shen X.-N., Ward D.J., Mahatme A., DeWitt J.L.
A novel 'patient-like' model of cholangiocarcinoma progression based on bile duct inoculation of tumorigenic rat cholangiocyte cell lines.
Hepatology 47:1178-1190(2008)

Cross-references
Encyclopedic resources Wikidata; Q54795815
Entry history
Entry creation02-May-2016
Last entry update10-Apr-2025
Version number11