ID   BDEneu
AC   CVCL_AS29
DR   Wikidata; Q54795815
RX   PubMed=16344070;
RX   PubMed=18081149;
CC   Doubling time: ~17-19 hours (PubMed=18081149).
CC   Genetic integration: Method=Transduction; Gene=RGD; 2561; Erbb2 (Note=With p.Val661Glu).
CC   Genetic integration: Method=Transduction; Gene=UniProtKB; P00552; Transposon Tn5 neo.
CC   Transformant: Activated Erbb2/neu.
CC   Derived from site: In situ; Bile duct; UBERON=UBERON_0002394.
CC   Cell type: Cholangiocyte; CL=CL_1000488.
CC   Breed/subspecies: Fischer 344; RS=RS:0000215.
OX   NCBI_TaxID=10116; ! Rattus norvegicus (Rat)
HI   CVCL_AS28 ! BDE1
SX   Male
CA   Transformed cell line
DT   Created: 02-05-16; Last updated: 19-12-24; Version: 10
//
RX   PubMed=16344070; DOI=10.1053/j.gastro.2005.10.010;
RA   Lai G.-H., Zhang Z.-C., Shen X.-N., Ward D.J., DeWitt J.L., Holt S.E.,
RA   Rozich R.A., Hixson D.C., Sirica A.E.;
RT   "erbB-2/neu transformed rat cholangiocytes recapitulate key cellular
RT   and molecular features of human bile duct cancer.";
RL   Gastroenterology 129:2047-2057(2005).
//
RX   PubMed=18081149; DOI=10.1002/hep.22088;
RA   Sirica A.E., Zhang Z.-C., Lai G.-H., Asano T., Shen X.-N., Ward D.J.,
RA   Mahatme A., DeWitt J.L.;
RT   "A novel 'patient-like' model of cholangiocarcinoma progression based
RT   on bile duct inoculation of tumorigenic rat cholangiocyte cell
RT   lines.";
RL   Hepatology 47:1178-1190(2008).
//