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Cellosaurus HL60 Ast.25 (CVCL_AR85)

[Text version]
Cell line name HL60 Ast.25
Synonyms HL60 Ast25
Accession CVCL_AR85
Resource Identification Initiative To cite this cell line use: HL60 Ast.25 (RRID:CVCL_AR85)
Comments Population: Caucasian.
Transformant: NCIt; C129638; Astatine-211 alpha radiation.
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Sequence variations
  • Gene deletion; HGNC; HGNC:11998; TP53; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:1787; CDKN2A; Simple; p.Arg80Ter (c.238C>T) (p.Pro94Leu, c.281C>T); ClinVar=VCV000009409; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:7989; NRAS; Simple; p.Gln61Leu (c.182A>T); ClinVar=VCV000375874; Zygosity=Heterozygous (from parent cell line).
Disease Adult acute myeloid leukemia (NCIt: C9154)
Acute myeloid leukemia (ORDO: Orphanet_519)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0002 (HL-60)
Sex of cell Female
Age at sampling 36Y
Category Cancer cell line
Publications

PubMed=6641827
Bunce C.M., Fisher A.G., Toksoz D., Brown G.
Isolation and characterisation of dimethylsulphoxide resistant variants from the human promyeloid cell line HL60.
Exp. Hematol. 11:828-833(1983)

Cross-references
Cell line databases/resources cancercelllines; CVCL_AR85
Encyclopedic resources Wikidata; Q54889825
Entry history
Entry creation02-May-2016
Last entry update19-Dec-2024
Version number18