ID   HL60 Ast.25
AC   CVCL_AR85
SY   HL60 Ast25
DR   cancercelllines; CVCL_AR85
DR   Wikidata; Q54889825
RX   PubMed=6641827;
CC   Population: Caucasian.
CC   Sequence variation: Gene deletion; HGNC; 11998; TP53; Zygosity=Homozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 1787; CDKN2A; Simple; p.Arg80Ter (c.238C>T) (p.Pro94Leu, c.281C>T); ClinVar=VCV000009409; Zygosity=Homozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 7989; NRAS; Simple; p.Gln61Leu (c.182A>T); ClinVar=VCV000375874; Zygosity=Heterozygous (from parent cell line).
CC   Transformant: NCIt; C129638; Astatine-211 alpha radiation.
CC   Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
DI   NCIt; C9154; Adult acute myeloid leukemia
DI   ORDO; Orphanet_519; Acute myeloid leukemia
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0002 ! HL-60
SX   Female
AG   36Y
CA   Cancer cell line
DT   Created: 02-05-16; Last updated: 05-10-23; Version: 17
//
RX   PubMed=6641827;
RA   Bunce C.M., Fisher A.G., Toksoz D., Brown G.;
RT   "Isolation and characterisation of dimethylsulphoxide resistant
RT   variants from the human promyeloid cell line HL60.";
RL   Exp. Hematol. 11:828-833(1983).
//