Cellosaurus HeLa-Mitotrap-Ap2a2-FKBP (CVCL_AR69)
| Cell line name | HeLa-Mitotrap-Ap2a2-FKBP |
|---|---|
| Accession | CVCL_AR69 |
| Resource Identification Initiative | To cite this cell line use: HeLa-Mitotrap-Ap2a2-FKBP (RRID:CVCL_AR69) |
| Comments | Population: African American. Characteristics: Transfected with Mitotrap, a construct composed of the import signal of yeast TOM70, a YFP and the rapamycin-binding (FRB) domain from MTOR. Genetic integration: Method=Transfection/transduction; Gene=HGNC; 562; AP2A2 (Note=Tagged with the FKBP domain from FKBP1A). Genetic integration: Method=Transfection/transduction; Gene=HGNC; 3942; MTOR (Note=With Met1_Arg2018del and Gln2114_Trp2549del = FRB). Transformant: NCBI_TaxID; 333761; Human papillomavirus type 18 (HPV18). Derived from site: In situ; Uterus, cervix; UBERON=UBERON_0000002. |
| Disease | Human papillomavirus-related cervical adenocarcinoma (NCIt: C27677) |
| Species of origin | Homo sapiens (Human) (NCBI Taxonomy: 9606) |
| Hierarchy | Parent: CVCL_AR66 (HeLa-Mitotrap) |
| Sex of cell | Female |
| Age at sampling | 30Y6M |
| Category | Cancer cell line |
| Web pages | http://www.enterprise.cam.ac.uk/reagents/hela-mitotrap-cell-lines/ |
| Publications | PubMed=20159602; DOI=10.1016/j.devcel.2009.12.015; PMCID=PMC2845799 |
| Cross-references | |
| Cell line collections (Providers) | Ximbio; 152428 |
| Encyclopedic resources | Wikidata; Q54882723 |
| Entry history | |
| Entry creation | 02-May-2016 |
| Last entry update | 10-Sep-2024 |
| Version number | 12 |