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Cellosaurus HHT4 (CVCL_A9Z1)

[Text version]
Cell line name HHT4
Synonyms HHT-4
Accession CVCL_A9Z1
Resource Identification Initiative To cite this cell line use: HHT4 (RRID:CVCL_A9Z1)
Comments Genetic integration: Method=Transduction; Gene=HGNC; HGNC:11730; TERT.
Genetic integration: Method=Transduction; Gene=UniProtKB; P00552; Transposon Tn5 neo.
Omics: Transcriptomics; Microarray.
Omics: Transcriptomics; RNAseq.
Derived from site: In situ; Liver; UBERON=UBERON_0002107.
Cell type: Hepatocyte; CL=CL_0000182.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling Adult
Category Telomerase immortalized cell line
Publications

PubMed=17404395; DOI=10.1093/carcin/bgm075
Budhu A., Chen Y., Kim J.W., Forgues M., Valerie K., Harris C.C., Wang X.-W.
Induction of a unique gene expression profile in primary human hepatocytes by hepatitis C virus core, NS3 and NS5A proteins.
Carcinogenesis 28:1552-1560(2007)

PubMed=20017137; DOI=10.1002/ijc.25118; PMCID=PMC2950321
Jiang W.-D., Wang X.-W., Unger T., Forgues M., Kim J.W., Hussain S.P., Bowman E., Spillare E.A., Lipsky M.M., Meck J.M., Cavalli L.R., Haddad B.R., Harris C.C.
Cooperation of tumor-derived HBx mutants and p53-249(ser) mutant in regulating cell proliferation, anchorage-independent growth and aneuploidy in a telomerase-immortalized normal human hepatocyte-derived cell line.
Int. J. Cancer 127:1011-1020(2010)

PubMed=32899426; DOI=10.3390/cancers12092510; PMCID=PMC7565451
Scherer D., Davila-Lopez M., Goeppert B., Abrahamsson S., Gonzalez Silos R., Nova I., Marcelain K., Roa J.C., Ibberson D., Umu S.U., Rounge T.B., Roessler S., Lorenzo-Bermejo J.
RNA sequencing of hepatobiliary cancer cell lines: data and applications to mutational and transcriptomic profiling.
Cancers (Basel) 12:2510.1-2510.14(2020)

Cross-references
Encyclopedic resources Wikidata; Q102114125
Entry history
Entry creation29-Oct-2020
Last entry update10-Apr-2025
Version number8