Cellosaurus CHO C1s-/- MGAT1- (CVCL_A9NX)
| Cell line name | CHO C1s-/- MGAT1- |
|---|---|
| Synonyms | C1s-/- MGAT1- CHO; CHO.K1.MGAT1-Prot-; CHO-s-MGAT1-Protease- |
| Accession | CVCL_A9NX |
| Resource Identification Initiative | To cite this cell line use: CHO C1s-/- MGAT1- (RRID:CVCL_A9NX) |
| Comments | Group: Serum/protein free medium cell line. Characteristics: This cell line minimizes proteolysis of clade B HIV-1 envelope proteins commonly observed in the production of monomeric gp120 and gp140 as well as gp140 trimers. Characteristics: This cell line can only produce N-linked carbohydrates with early oligomannose glycans (Man5-9). Knockout cell: Method=CRISPR/Cas9; UniProtKB; Q924C0; Mgat1. Knockout cell: Method=CRISPR/Cas9; UniProtKB; G3GUR0; C1s. Derived from site: In situ; Ovary; UBERON=UBERON_0000992. Cell type: Epithelial cell of ovary; CL=CL_2000064. |
| Species of origin | Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) (NCBI Taxonomy: 10029) |
| Hierarchy | Parent: CVCL_VP59 (CHO MGAT1-) |
| Sex of cell | Female |
| Age at sampling | Adult |
| Category | Spontaneously immortalized cell line |
| Publications | PubMed=31087560; DOI=10.1002/bit.27016 |
| Cross-references | |
| Cell line collections (Providers) | HIVReagentProgram; ARP-13574 |
| Encyclopedic resources | Wikidata; Q108820026 |
| Entry history | |
| Entry creation | 23-Sep-2021 |
| Last entry update | 30-Jan-2024 |
| Version number | 5 |