Cellosaurus cell line SK-N-BE(1)n (CVCL

Cellosaurus SK-N-BE(1)n (CVCL_A8RV)

Cross-references
Cell line name	SK-N-BE(1)n
Synonyms	SKNBE(1)N; SKNBE(1n); SKNBE1n
Accession	CVCL_A8RV
Resource Identification Initiative	To cite this cell line use: SK-N-BE(1)n (RRID:CVCL_A8RV)
Comments	From: Memorial Sloan Kettering Cancer Center; New York; USA. Population: Caucasian. Characteristics: Neuroblastic type (N-type) (PubMed=15720811). Karyotypic information: 46,XY,del(1)(p32),der(3)t(3;17)(p21;q21),der(4)t(1;4)(q21;q3?5),dmin (PubMed=11196202). Derived from site: Metastatic; Bone marrow; UBERON=UBERON_0002371.
Sequence variations	Mutation; HGNC; 11998; TP53; None_reported; -; Zygosity=- (PubMed=11196202).
Disease	Neuroblastoma (NCIt: C3270) Neuroblastoma (ORDO: Orphanet_635)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy	Parent: CVCL_9898 (SK-N-BE(1))
Sex of cell	Male
Age at sampling	1Y10M
Category	Cancer cell line
Publications	PubMed=2535691 Ciccarone V.C., Spengler B.A., Meyers M.B., Biedler J.L., Ross R.A. Phenotypic diversification in human neuroblastoma cells: expression of distinct neural crest lineages. Cancer Res. 49:219-225(1989) PubMed=11196202 Tweddle D.A., Malcolm A.J., Bown N., Pearson A.D.J., Lunec J. Evidence for the development of p53 mutations after cytotoxic therapy in a neuroblastoma cell line. Cancer Res. 61:8-13(2001) PubMed=15720811; DOI=10.1593/neo.04310 Walton J.D., Kattan D.R., Thomas S.K., Spengler B.A., Guo H.-F., Biedler J.L., Cheung N.-K.V., Ross R.A. Characteristics of stem cells from human neuroblastoma cell lines and in tumors. Neoplasia 6:838-845(2004) PubMed=26342562; DOI=10.1016/j.scr.2015.08.008 Ross R.A., Walton J.D., Han D., Guo H.-F., Cheung N.-K.V. A distinct gene expression signature characterizes human neuroblastoma cancer stem cells. Stem Cell Res. 15:419-426(2015)
Encyclopedic resources	Wikidata; Q108821307
Polymorphism and mutation databases	IARC_TP53; 23829
Entry history
Entry creation	23-Sep-2021
Last entry update	29-Jun-2023
Version number	5