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Cellosaurus SK-N-BE(1)n (CVCL_A8RV)

[Text version]
Cell line name SK-N-BE(1)n
Synonyms SKNBE(1)N; SKNBE(1n); SKNBE1n
Accession CVCL_A8RV
Resource Identification Initiative To cite this cell line use: SK-N-BE(1)n (RRID:CVCL_A8RV)
Comments From: Memorial Sloan Kettering Cancer Center; New York; USA.
Population: Caucasian.
Characteristics: Neuroblastic type (N-type) (PubMed=15720811).
Karyotypic information: 46,XY,del(1)(p32),der(3)t(3;17)(p21;q21),der(4)t(1;4)(q21;q3?5),dmin (PubMed=11196202).
Derived from site: Metastatic; Bone marrow; UBERON=UBERON_0002371.
Sequence variations
Disease Neuroblastoma (NCIt: C3270)
Neuroblastoma (ORDO: Orphanet_635)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_9898 (SK-N-BE(1))
Sex of cell Male
Age at sampling 1Y10M
Category Cancer cell line
Publications

PubMed=2535691
Ciccarone V.C., Spengler B.A., Meyers M.B., Biedler J.L., Ross R.A.
Phenotypic diversification in human neuroblastoma cells: expression of distinct neural crest lineages.
Cancer Res. 49:219-225(1989)

PubMed=11196202
Tweddle D.A., Malcolm A.J., Bown N., Pearson A.D.J., Lunec J.
Evidence for the development of p53 mutations after cytotoxic therapy in a neuroblastoma cell line.
Cancer Res. 61:8-13(2001)

PubMed=15720811; DOI=10.1593/neo.04310; PMCID=PMC1531688
Walton J.D., Kattan D.R., Thomas S.K., Spengler B.A., Guo H.-F., Biedler J.L., Cheung N.-K.V., Ross R.A.
Characteristics of stem cells from human neuroblastoma cell lines and in tumors.
Neoplasia 6:838-845(2004)

PubMed=26342562; DOI=10.1016/j.scr.2015.08.008; PMCID=PMC4601571
Ross R.A., Walton J.D., Han D., Guo H.-F., Cheung N.-K.V.
A distinct gene expression signature characterizes human neuroblastoma cancer stem cells.
Stem Cell Res. 15:419-426(2015)

Cross-references
Encyclopedic resources Wikidata; Q108821307
Polymorphism and mutation databases IARC_TP53; 23829
Entry history
Entry creation23-Sep-2021
Last entry update19-Dec-2024
Version number6