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Cellosaurus SK-N-BE(1) (CVCL_9898)

[Text version]
Cell line name SK-N-BE(1)
Synonyms SK-N-Be(1); SKNBE(1); SKNBE-1; SKNBE1
Accession CVCL_9898
Resource Identification Initiative To cite this cell line use: SK-N-BE(1) (RRID:CVCL_9898)
Comments From: Memorial Sloan Kettering Cancer Center; New York; USA.
Population: Caucasian.
Doubling time: ~4 days (PubMed=29704); 96 hours (COG).
Omics: Transcriptome analysis by microarray.
Derived from site: Metastatic; Bone marrow; UBERON=UBERON_0002371.
Disease Neuroblastoma (NCIt: C3270)
Neuroblastoma (ORDO: Orphanet_635)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_A8RV (SK-N-BE(1)n)CVCL_A8RW (SK-N-BE(1)s)
Originate from same individual CVCL_0528 ! SK-N-BE(2)
Sex of cell Male
Age at sampling 1Y10M
Category Cancer cell line
STR profile Source(s): COG

Markers:
AmelogeninX,Y
CSF1PO10
D2S133817,23
D3S135819
D5S81812
D7S8209,10
D8S117913,14
D13S31711
D16S5399,11
D18S5114,16
D19S43312,13
D21S1130,32.2
FGA22,25
TH016
TPOX8,11
vWA18

Run an STR similarity search on this cell line
Web pages http://www.cccells.org/dl/NB_Data_Sheets/SK-N-BE1_Cell_Line_Data_Sheet_COGcell_org.pdf
Publications

PubMed=29704
Biedler J.L., Roffler-Tarlov S., Schachner M., Freedman L.S.
Multiple neurotransmitter synthesis by human neuroblastoma cell lines and clones.
Cancer Res. 38:3751-3757(1978)

DOI=10.1016/B978-0-12-008304-6.50015-4
Biedler J.L., Meyers M.B., Spengler B.A.
Homogeneously staining regions and double minute chromosomes, prevalent cytogenetic abnormalities of human neuroblastoma cells.
(In book chapter) Advances in cellular neurobiology, Vol. 4; Fedoroff S., Hertz L. (eds.); pp.267-307; Academic Press; New York; USA (1983)

PubMed=2535691
Ciccarone V.C., Spengler B.A., Meyers M.B., Biedler J.L., Ross R.A.
Phenotypic diversification in human neuroblastoma cells: expression of distinct neural crest lineages.
Cancer Res. 49:219-225(1989)

DOI=10.1007/0-306-46872-7_2
Thiele C.J.
Neuroblastoma.
(In book chapter) Human cell culture. Vol. 1. Cancer cell lines part 1; Masters J.R.W., Palsson B.O. (eds.); pp.21-53; Kluwer Academic Publishers; New York; USA (1999)

PubMed=11507071
Keshelava N., Zuo J.J., Chen P., Waidyaratne S.N., Luna M.C., Gomer C.J., Triche T.J., Reynolds C.P.
Loss of p53 function confers high-level multidrug resistance in neuroblastoma cell lines.
Cancer Res. 61:6185-6193(2001)

PubMed=24792489; DOI=10.1007/s11060-014-1456-8
Farooqi A.S., Dagg R.A., Choi L.M.R., Shay J.W., Reynolds C.P., Lau L.M.S.
Alternative lengthening of telomeres in neuroblastoma cell lines is associated with a lack of MYCN genomic amplification and with p53 pathway aberrations.
J. Neurooncol. 119:17-26(2014)

Cross-references
Encyclopedic resources Wikidata; Q54954440
Entry history
Entry creation06-Jun-2012
Last entry update02-May-2024
Version number23