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Cellosaurus SBKMS-KS1 (CVCL_A8HX)

[Text version]
Cell line name SBKMS-KS1
Synonyms SBKMSKS1; SBSR-AKS
Accession CVCL_A8HX
Resource Identification Initiative To cite this cell line use: SBKMS-KS1 (RRID:CVCL_A8HX)
Comments Derived from site: Metastatic; Groin; UBERON=UBERON_0008337.
Sequence variations
  • Gene fusion; HGNC; 3508; EWSR1 + HGNC; 3749; FLI1; Name(s)=EWSR1-FLI1, EWS-FLI1; Note=Type 1 fusion (Ex7/Ex6) (PubMed=19289832).
Disease Ewing sarcoma (NCIt: C4817)
Ewing sarcoma (ORDO: Orphanet_319)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 17Y
Category Cancer cell line
Publications

PubMed=19289832; DOI=10.1073/pnas.0810759106; PMCID=PMC2656557
Richter G.H.S., Plehm S., Fasan A., Rossler S., Unland R., Bennani-Baiti I.M., Hotfilder M., Lowel D., von Luettichau I., Mossbrugger I., Quintanilla-Martinez de Fend L., Kovar H., Staege M.S., Muller-Tidow C., Burdach S.
EZH2 is a mediator of EWS/FLI1 driven tumor growth and metastasis blocking endothelial and neuro-ectodermal differentiation.
Proc. Natl. Acad. Sci. U.S.A. 106:5324-5329(2009)

PubMed=22080479; DOI=10.1158/1541-7786.MCR-11-0524
Grunewald T.G.P., Diebold I., Esposito I., Plehm S., Hauer K., Thiel U., da Silva-Buttkus P., Neff F., Unland R., Muller-Tidow C., Zobywalski C., Lohrig K., Lewandrowski U., Sickmann A., Prazeres da Costa O., Gorlach A., Cossarizza A., Butt E., Richter G.H.S., Burdach S.
STEAP1 is associated with the invasive and oxidative stress phenotype of Ewing tumors.
Mol. Cancer Res. 10:52-65(2012)

DOI=10.5282/edoc.27750
Orth M.F.
Systematic multi-omics profiling of Ewing sarcoma cell lines.
Thesis PhD (2021); Ludwig Maximilians University of Munich; Munich; Germany

Cross-references
Encyclopedic resources Wikidata; Q107116850
Entry history
Entry creation20-May-2021
Last entry update29-Jun-2023
Version number4