ID   SBKMS-KS1
AC   CVCL_A8HX
SY   SBKMSKS1; SBSR-AKS
DR   Wikidata; Q107116850
RX   DOI=10.5282/edoc.27750;
RX   PubMed=19289832;
RX   PubMed=22080479;
CC   Sequence variation: Gene fusion; HGNC; 3508; EWSR1 + HGNC; 3749; FLI1; Name(s)=EWSR1-FLI1, EWS-FLI1; Note=Type 1 fusion (Ex7/Ex6) (PubMed=19289832).
CC   Derived from site: Metastatic; Groin; UBERON=UBERON_0008337.
DI   NCIt; C4817; Ewing sarcoma
DI   ORDO; Orphanet_319; Ewing sarcoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Female
AG   17Y
CA   Cancer cell line
DT   Created: 20-05-21; Last updated: 29-06-23; Version: 4
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RX   DOI=10.5282/edoc.27750;
RA   Orth M.F.;
RT   "Systematic multi-omics profiling of Ewing sarcoma cell lines.";
RL   Thesis PhD (2021); Ludwig Maximilians University of Munich; Munich; Germany.
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RX   PubMed=19289832; DOI=10.1073/pnas.0810759106; PMCID=PMC2656557;
RA   Richter G.H.S., Plehm S., Fasan A., Rossler S., Unland R.,
RA   Bennani-Baiti I.M., Hotfilder M., Lowel D., von Luettichau I.,
RA   Mossbrugger I., Quintanilla-Martinez de Fend L., Kovar H.,
RA   Staege M.S., Muller-Tidow C., Burdach S.;
RT   "EZH2 is a mediator of EWS/FLI1 driven tumor growth and metastasis
RT   blocking endothelial and neuro-ectodermal differentiation.";
RL   Proc. Natl. Acad. Sci. U.S.A. 106:5324-5329(2009).
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RX   PubMed=22080479; DOI=10.1158/1541-7786.MCR-11-0524;
RA   Grunewald T.G.P., Diebold I., Esposito I., Plehm S., Hauer K., Thiel U.,
RA   da Silva-Buttkus P., Neff F., Unland R., Muller-Tidow C.,
RA   Zobywalski C., Lohrig K., Lewandrowski U., Sickmann A.,
RA   Prazeres da Costa O., Gorlach A., Cossarizza A., Butt E.,
RA   Richter G.H.S., Burdach S.;
RT   "STEAP1 is associated with the invasive and oxidative stress phenotype
RT   of Ewing tumors.";
RL   Mol. Cancer Res. 10:52-65(2012).
//