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Cellosaurus SAS-R (CVCL_A8GP)

[Text version]
Cell line name SAS-R
Synonyms SAS-R1
Accession CVCL_A8GP
Resource Identification Initiative To cite this cell line use: SAS-R (RRID:CVCL_A8GP)
Comments Population: Japanese.
Characteristics: Radioresistant. Can proliferate with daily exposure to 2 Gy X-rays for more than 30 days (PubMed=21716292).
Transformant: NCIt; C17262; X-Ray.
Derived from site: In situ; Oral cavity, tongue; UBERON=UBERON_0001723.
Disease Tongue squamous cell carcinoma (NCIt: C4648)
Squamous cell carcinoma of the oral tongue (ORDO: Orphanet_457252)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_1675 (SAS)
Sex of cell Female
Age at sampling 69Y
Category Cancer cell line
STR profile Source(s): TKG=TKG 0800

Markers:
AmelogeninX
CSF1PO11
D5S8189
D7S82011,12
D13S31710,12
D16S53912,13
TH016,7
TPOX11,12
vWA14,17

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Publications

PubMed=20410675; DOI=10.1269/jrr.09094
Kuwahara Y., Mori M., Oikawa T., Shimura T., Ohtake Y., Mori S., Ohkubo Y., Fukumoto M.
The modified high-density survival assay is the useful tool to predict the effectiveness of fractionated radiation exposure.
J. Radiat. Res. 51:297-302(2010)

PubMed=21716292; DOI=10.1038/cddis.2011.56; PMCID=PMC3168998
Kuwahara Y., Oikawa T., Ochiai Y., Roudkenar M.H., Fukumoto M., Shimura T., Ohtake Y., Ohkubo Y., Mori S., Uchiyama Y., Fukumoto M.
Enhancement of autophagy is a potential modality for tumors refractory to radiotherapy.
Cell Death Dis. 2:e177.1-e177.11(2011)

PubMed=27681752; DOI=10.1016/j.ijrobp.2016.07.002
Kuwahara Y., Roudkenar M.H., Suzuki M., Urushihara Y., Fukumoto M., Saito Y., Fukumoto M.
The involvement of mitochondrial membrane potential in cross-resistance between radiation and docetaxel.
Int. J. Radiat. Oncol. Biol. Phys. 96:556-565(2016)

Cross-references
Cell line collections (Providers) TKG; TKG 0800
Encyclopedic resources Wikidata; Q107116847
Entry history
Entry creation20-May-2021
Last entry update02-May-2024
Version number5