| Cell line name |
SCL-I |
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| Synonyms |
SCL I; SCL-1; SCL1 |
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| Accession |
CVCL_A789 |
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| Resource Identification Initiative |
To cite this cell line use: SCL-I (RRID:CVCL_A789) |
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| Comments |
Population: Caucasian.
Doubling time: ~50-60 hours (CLS=300496).
Derived from site: In situ; Face, skin; UBERON=UBERON_1000021. |
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| Sequence variations |
- Mutation; HGNC; 11998; TP53; Simple; p.Val197Ter; Zygosity=Unspecified (PubMed=11992403).
|
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| Disease |
Skin squamous cell carcinoma (NCIt: C4819) |
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| Species of origin |
Homo sapiens (Human)
(NCBI Taxonomy: 9606) |
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| Hierarchy |
Children:
|
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| Sex of cell |
Female |
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| Age at sampling |
74Y |
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| Category |
Cancer cell line |
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| STR profile |
Source(s): CLS=300496
Markers:| Amelogenin | X |
| CSF1PO | 10,11 |
| D3S1358 | 16,17 |
| D5S818 | 11,12 |
| D7S820 | 11 |
| D8S1179 | 13,14 |
| D13S317 | 9,11 |
| D16S539 | 9,12 |
| D18S51 | 16,19 |
| D21S11 | 29,30 |
| FGA | 21 |
| Penta D | 13,14 |
| Penta E | 12 |
| TH01 | 6,9.3 |
| TPOX | 8,11 |
| vWA | 16,18 |
Run an STR similarity search on this cell line |
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| Publications | PubMed=6950169; DOI=10.1093/jnci/68.3.415
Boukamp P., Tilgen W., Dzarlieva-Petrusevska R.T., Breitkreutz D., Haag D., Riehl R.K., Bohnert A., Fusenig N.E.
Phenotypic and genotypic characteristics of a cell line from a squamous cell carcinoma of human skin.
J. Natl. Cancer Inst. 68:415-427(1982) PubMed=6196111
Tilgen W., Boukamp P., Breitkreutz D., Dzarlieva-Petrusevska R.T., Engstner M., Haag D., Fusenig N.E.
Preservation of morphological, functional, and karyotypic traits during long-term culture and in vivo passage of two human skin squamous cell carcinomas.
Cancer Res. 43:5995-6011(1983) PubMed=2293663; DOI=10.1128/JVI.64.1.215-221.1990; PMCID=PMC249089
Chesebro B.W., Buller R., Portis J.L., Wehrly K.
Failure of human immunodeficiency virus entry and infection in CD4-positive human brain and skin cells.
J. Virol. 64:215-221(1990) PubMed=11992403; DOI=10.1002/ijc.10321
Popp S., Waltering S., Herbst C., Moll I., Boukamp P.
UV-B-type mutations and chromosomal imbalances indicate common pathways for the development of Merkel and skin squamous cell carcinomas.
Int. J. Cancer 99:352-360(2002) |
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| Cross-references |
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| Cell line collections (Providers) |
CLS; 300496
|
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| Chemistry resources |
ChEMBL-Cells; CHEMBL3307442
ChEMBL-Targets; CHEMBL614903
PubChem_Cell_line; CVCL_A789
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| Encyclopedic resources |
Wikidata; Q54952439
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| Polymorphism and mutation databases |
Cosmic; 740987
|
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| Entry history |
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| Entry creation | 06-Jun-2012 |
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| Last entry update | 02-May-2024 |
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| Version number | 17 |
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