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Cellosaurus U2OS SQSTM1 KO (CVCL_A6LP)

[Text version]
Cell line name U2OS SQSTM1 KO
Accession CVCL_A6LP
Resource Identification Initiative To cite this cell line use: U2OS SQSTM1 KO (RRID:CVCL_A6LP)
Comments Population: Caucasian.
Knockout cell: Method=CRISPR/Cas9; HGNC; HGNC:11280; SQSTM1.
Derived from site: In situ; Bone, tibia; UBERON=UBERON_0000979.
Sequence variations
  • Mutation; HGNC; HGNC:9277; PPM1D; Simple; p.Arg458Ter (c.1372C>T); ClinVar=VCV002445214; Zygosity=Heterozygous (from parent cell line).
Disease Osteosarcoma (NCIt: C9145)
Osteosarcoma (ORDO: Orphanet_668)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0042 (U2OS)
Sex of cell Female
Age at sampling 15Y
Category Cancer cell line
Publications

PubMed=39006307; DOI=10.12688/f1000research.132628.2; PMCID=PMC11240082
Ayoubi R., Alshafie W., Shlaifer I., Southern K., McPherson P.S., Laflamme C.
NeuroSGC/YCharOS Collaborative Group
The identification of high-performing antibodies for sequestosome-1 for use in western blot, immunoprecipitation and immunofluorescence.
F1000Research 12:324.1-324.14(2023)

Cross-references
Encyclopedic resources Wikidata; Q107117178
Entry history
Entry creation20-May-2021
Last entry update19-Dec-2024
Version number7