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Cellosaurus OHN-GM (CVCL_A662)

[Text version]
Cell line name OHN-GM
Synonyms OHNGM
Accession CVCL_A662
Resource Identification Initiative To cite this cell line use: OHN-GM (RRID:CVCL_A662)
Comments Population: Japanese.
Characteristics: CSF2 dependent.
Doubling time: ~60 hours (PubMed=9266938).
Omics: SNP array analysis.
Donor information: Originally the patient was suffering from Hodgkin lymphoma.
Derived from site: In situ; Bone marrow; UBERON=UBERON_0002371.
Sequence variations
Disease Myelodysplastic syndrome (NCIt: C3247)
Therapy-related acute myeloid leukemia (NCIt: C8252)
Therapy related acute myeloid leukemia and myelodysplastic syndrome (ORDO: Orphanet_86846)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 60Y
Category Cancer cell line
Publications

PubMed=9266938; DOI=10.1046/j.1365-2141.1997.2413058.x
Nagai M., Fujita M., Ikeda T., Ohmori M., Kuwabara H., Yamaoka G., Tanaka K., Kamada N., Taniwaki M., Inoue T., Irino S., Takahara J.
Alterations of p53 and Rb genes in a novel human GM-CSF-dependent myeloid cell line (OHN-GM) established from therapy-related leukaemia.
Br. J. Haematol. 98:392-398(1997)

DOI=10.1016/B978-0-12-221970-2.50457-5
Drexler H.G.
The leukemia-lymphoma cell line factsbook.
(In book) ISBN 9780122219702; pp.1-733; Academic Press; London; United Kingdom (2001)

PubMed=27750403; DOI=10.1002/gcc.22430
Palau A., Mallo M., Palomo L., Rodriguez-Hernandez I., Diesch J., Campos D., Granada I., Junca J., Drexler H.G., Sole F., Buschbeck M.
Immunophenotypic, cytogenetic, and mutational characterization of cell lines derived from myelodysplastic syndrome patients after progression to acute myeloid leukemia.
Genes Chromosomes Cancer 56:243-252(2017)

PubMed=29533902; DOI=10.1515/hsz-2017-0321
Drexler H.G., Pommerenke C., Eberth S., Nagel S.
Hodgkin lymphoma cell lines: to separate the wheat from the chaff.
Biol. Chem. 399:511-523(2018)

Cross-references
Cell line databases/resources cancercelllines; CVCL_A662
Encyclopedic resources Wikidata; Q54931895
Gene expression databases GEO; GSM2124119
Polymorphism and mutation databases Cosmic; 787473
Cosmic; 975295
Cosmic; 1281350
Progenetix; CVCL_A662
Entry history
Entry creation06-Jun-2012
Last entry update19-Dec-2024
Version number17