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Cellosaurus MR-87 (CVCL_A655)

[Text version]
Cell line name MR-87
Accession CVCL_A655
Resource Identification Initiative To cite this cell line use: MR-87 (RRID:CVCL_A655)
Comments Population: Japanese.
Doubling time: 120-144 hours (PubMed=3048438).
Derived from site: In situ; Bone marrow; UBERON=UBERON_0002371.
Sequence variations
Disease Childhood B acute lymphoblastic leukemia with t(9;22)(q34.1;q11.2) BCR-ABL1 (NCIt: C68659)
B-lymphoblastic leukemia/lymphoma with t(9;22)(q34.1;q11.2) (ORDO: Orphanet_585909)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_QW99 ! MR-B
Sex of cell Male
Age at sampling 4Y
Category Cancer cell line
Publications

PubMed=3048438; DOI=10.1182/blood.V72.4.1261.1261
Okamura J., Yamada S., Ishii E., Hara T., Takahira H., Nishimura J., Yumura K., Kawa-Ha K., Takase K., Enomoto Y., Tasaka H.
A novel leukemia cell line, MR-87, with positive Philadelphia chromosome and negative breakpoint cluster region rearrangement coexpressing myeloid and early B-cell markers.
Blood 72:1261-1268(1988)

PubMed=1884023; DOI=10.1182/blood.V78.6.1574.1574
Okabe M., Kunieda Y., Sugiwura T., Tanaka M., Miyagishima T., Saiki I., Minagawa T., Kurosawa M., Itaya T., Miyazaki T.
Inhibitory effect of interleukin-4 on the in vitro growth of Ph1-positive acute lymphoblastic leukemia cells.
Blood 78:1574-1580(1991)

PubMed=10071072; DOI=10.1016/S0145-2126(98)00171-4
Drexler H.G., MacLeod R.A.F., Uphoff C.C.
Leukemia cell lines: in vitro models for the study of Philadelphia chromosome-positive leukemia.
Leuk. Res. 23:207-215(1999)

PubMed=10576511; DOI=10.1016/S0145-2126(99)00131-9
Uphoff C.C., Habig S., Fombonne S., Matsuo Y., Drexler H.G.
ABL-BCR expression in BCR-ABL-positive human leukemia cell lines.
Leuk. Res. 23:1055-1060(1999)

DOI=10.1016/B978-0-12-221970-2.50457-5
Drexler H.G.
The leukemia-lymphoma cell line factsbook.
(In book) ISBN 9780122219702; pp.1-733; Academic Press; London; United Kingdom (2001)

Cross-references
Encyclopedic resources Wikidata; Q54906561
Polymorphism and mutation databases Cosmic; 787460
Cosmic; 975279
Cosmic; 999768
Entry history
Entry creation06-Jun-2012
Last entry update19-Dec-2024
Version number16