ID   MR-87
AC   CVCL_A655
DR   Cosmic; 787460
DR   Cosmic; 975279
DR   Cosmic; 999768
DR   Wikidata; Q54906561
RX   DOI=10.1016/B978-0-12-221970-2.50457-5;
RX   PubMed=1884023;
RX   PubMed=3048438;
RX   PubMed=10071072;
RX   PubMed=10576511;
CC   Population: Japanese.
CC   Doubling time: 120-144 hours (PubMed=3048438).
CC   Sequence variation: Gene fusion; HGNC; HGNC:76; ABL1 + HGNC; HGNC:1014; BCR; Name(s)=BCR-ABL1, BCR-ABL (PubMed=3048438; PubMed=10071072; PubMed=10576511).
CC   Derived from site: In situ; Bone marrow; UBERON=UBERON_0002371.
DI   NCIt; C68659; Childhood B acute lymphoblastic leukemia with t(9;22)(q34.1;q11.2) BCR-ABL1
DI   ORDO; Orphanet_585909; B-lymphoblastic leukemia/lymphoma with t(9;22)(q34.1;q11.2)
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
OI   CVCL_QW99 ! MR-B
SX   Male
AG   4Y
CA   Cancer cell line
DT   Created: 06-06-12; Last updated: 19-12-24; Version: 16
//
RX   DOI=10.1016/B978-0-12-221970-2.50457-5;
RA   Drexler H.G.;
RT   "The leukemia-lymphoma cell line factsbook.";
RL   (In book) ISBN 9780122219702; pp.1-733; Academic Press; London; United Kingdom (2001).
//
RX   PubMed=1884023; DOI=10.1182/blood.V78.6.1574.1574;
RA   Okabe M., Kunieda Y., Sugiwura T., Tanaka M., Miyagishima T., Saiki I.,
RA   Minagawa T., Kurosawa M., Itaya T., Miyazaki T.;
RT   "Inhibitory effect of interleukin-4 on the in vitro growth of
RT   Ph1-positive acute lymphoblastic leukemia cells.";
RL   Blood 78:1574-1580(1991).
//
RX   PubMed=3048438; DOI=10.1182/blood.V72.4.1261.1261;
RA   Okamura J., Yamada S., Ishii E., Hara T., Takahira H., Nishimura J.,
RA   Yumura K., Kawa-Ha K., Takase K., Enomoto Y., Tasaka H.;
RT   "A novel leukemia cell line, MR-87, with positive Philadelphia
RT   chromosome and negative breakpoint cluster region rearrangement
RT   coexpressing myeloid and early B-cell markers.";
RL   Blood 72:1261-1268(1988).
//
RX   PubMed=10071072; DOI=10.1016/S0145-2126(98)00171-4;
RA   Drexler H.G., MacLeod R.A.F., Uphoff C.C.;
RT   "Leukemia cell lines: in vitro models for the study of Philadelphia
RT   chromosome-positive leukemia.";
RL   Leuk. Res. 23:207-215(1999).
//
RX   PubMed=10576511; DOI=10.1016/S0145-2126(99)00131-9;
RA   Uphoff C.C., Habig S., Fombonne S., Matsuo Y., Drexler H.G.;
RT   "ABL-BCR expression in BCR-ABL-positive human leukemia cell lines.";
RL   Leuk. Res. 23:1055-1060(1999).
//