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Cellosaurus L-MAT (CVCL_A640)

[Text version]
Cell line name L-MAT
Accession CVCL_A640
Resource Identification Initiative To cite this cell line use: L-MAT (RRID:CVCL_A640)
Comments Population: Japanese.
Sequence variations
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg196Glufs*51 (c.586delC); Zygosity=Unspecified (PubMed=10071127).
Disease Childhood T acute lymphoblastic leukemia (NCIt: C7953)
Precursor T-cell acute lymphoblastic leukemia (ORDO: Orphanet_99861)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Category Cancer cell line
Publications

PubMed=8558913
Morita S., Tsuchiya S., Fujie H., Itano M., Ohashi Y., Minegishi M., Imaizumi M., Endo M., Takano N., Konno T.
Cell surface c-kit receptors in human leukemia cell lines and pediatric leukemia: selective preservation of c-kit expression on megakaryoblastic cell lines during adaptation to in vitro culture.
Leukemia 10:102-105(1996)

PubMed=10071127; DOI=10.1016/S0145-2126(98)00146-5
Kawamura M., Ohnishi H., Guo S.-X., Sheng X.-M., Minegishi M., Hanada R., Horibe K., Hongo T., Kaneko Y., Bessho F., Yanagisawa M., Sekiya T., Hayashi Y.
Alterations of the p53, p21, p16, p15 and RAS genes in childhood T-cell acute lymphoblastic leukemia.
Leuk. Res. 23:115-126(1999)

PubMed=15691325; DOI=10.1111/j.1742-4658.2004.04519.x
Ahmed S., Shibazaki M., Takeuchi T., Kikuchi H.
Protein kinase Ctheta activity is involved in the 2,3,7,8-tetrachlorodibenzo-p-dioxin-induced signal transduction pathway leading to apoptosis in L-MAT, a human lymphoblastic T-cell line.
FEBS J. 272:903-915(2005)

Cross-references
Encyclopedic resources Wikidata; Q54900906
Polymorphism and mutation databases Cosmic; 721717
Cosmic; 1375580
IARC_TP53; 10572
Entry history
Entry creation06-Jun-2012
Last entry update19-Dec-2024
Version number10