ID   L-MAT
AC   CVCL_A640
DR   Cosmic; 721717
DR   Cosmic; 1375580
DR   IARC_TP53; 10572
DR   Wikidata; Q54900906
RX   PubMed=8558913;
RX   PubMed=10071127;
RX   PubMed=15691325;
CC   Population: Japanese.
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg196Glufs*51 (c.586delC); Zygosity=Unspecified (PubMed=10071127).
DI   NCIt; C7953; Childhood T acute lymphoblastic leukemia
DI   ORDO; Orphanet_99861; Precursor T-cell acute lymphoblastic leukemia
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
CA   Cancer cell line
DT   Created: 06-06-12; Last updated: 19-12-24; Version: 10
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RX   PubMed=8558913;
RA   Morita S., Tsuchiya S., Fujie H., Itano M., Ohashi Y., Minegishi M.,
RA   Imaizumi M., Endo M., Takano N., Konno T.;
RT   "Cell surface c-kit receptors in human leukemia cell lines and
RT   pediatric leukemia: selective preservation of c-kit expression on
RT   megakaryoblastic cell lines during adaptation to in vitro culture.";
RL   Leukemia 10:102-105(1996).
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RX   PubMed=10071127; DOI=10.1016/S0145-2126(98)00146-5;
RA   Kawamura M., Ohnishi H., Guo S.-X., Sheng X.-M., Minegishi M.,
RA   Hanada R., Horibe K., Hongo T., Kaneko Y., Bessho F., Yanagisawa M.,
RA   Sekiya T., Hayashi Y.;
RT   "Alterations of the p53, p21, p16, p15 and RAS genes in childhood
RT   T-cell acute lymphoblastic leukemia.";
RL   Leuk. Res. 23:115-126(1999).
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RX   PubMed=15691325; DOI=10.1111/j.1742-4658.2004.04519.x;
RA   Ahmed S., Shibazaki M., Takeuchi T., Kikuchi H.;
RT   "Protein kinase Ctheta activity is involved in the
RT   2,3,7,8-tetrachlorodibenzo-p-dioxin-induced signal transduction
RT   pathway leading to apoptosis in L-MAT, a human lymphoblastic T-cell
RT   line.";
RL   FEBS J. 272:903-915(2005).
//