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Cellosaurus KMO-90 (CVCL_A636)

[Text version]
Cell line name KMO-90
Accession CVCL_A636
Resource Identification Initiative To cite this cell line use: KMO-90 (RRID:CVCL_A636)
Comments Population: Japanese.
Doubling time: ~72 hours (PubMed=8412323).
Derived from site: In situ; Bone marrow; UBERON=UBERON_0002371.
Sequence variations
Disease Childhood B acute lymphoblastic leukemia (NCIt: C9140)
B acute lymphoblastic leukemia with t(1;19)(q23;p13.3) E2A-PBX1 (TCF3-PBX1) (NCIt: C80347)
B-lymphoblastic leukemia/lymphoma with t(1;19)(q23;p13.3) (ORDO: Orphanet_585956)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_QW97 ! KMO-R
Sex of cell Female
Age at sampling 12Y
Category Cancer cell line
Publications

PubMed=8372807; DOI=10.1002/ajh.2830430404
Sotomatsu M., Yugami S.-i., Shitara T., Kuroume T.
Dipyridamole enhancement of drug sensitivity in acute lymphoblastic leukemia cells.
Am. J. Hematol. 43:251-255(1993)

PubMed=8412323
Sotomatsu M., Hayashi Y., Kawamura M., Yugami S.-i., Shitara T.
Establishment of a new human pre-B acute lymphoblastic leukemia cell line (KMO-90) with 1;19 translocation carrying p53 gene alterations.
Leukemia 7:1615-1620(1993)

PubMed=7727782; DOI=10.1182/blood.V85.9.2546.bloodjournal8592546
Kawamura M., Kikuchi A., Kobayashi S., Hanada R., Yamamoto K., Horibe K., Shikano T., Ueda K., Hayashi K., Sekiya T., Hayashi Y.
Mutations of the p53 and ras genes in childhood t(1;19)-acute lymphoblastic leukemia.
Blood 85:2546-2552(1995)

PubMed=10637496; DOI=10.1038/sj.leu.2401604
Drexler H.G., Fombonne S., Matsuo Y., Hu Z.-B., Hamaguchi H., Uphoff C.C.
p53 alterations in human leukemia-lymphoma cell lines: in vitro artifact or prerequisite for cell immortalization?
Leukemia 14:198-206(2000)

DOI=10.1016/B978-0-12-221970-2.50457-5
Drexler H.G.
The leukemia-lymphoma cell line factsbook.
(In book) ISBN 9780122219702; pp.1-733; Academic Press; London; United Kingdom (2001)

Cross-references
Cell line databases/resources cancercelllines; CVCL_A636
Encyclopedic resources Wikidata; Q54900128
Polymorphism and mutation databases Cosmic; 710458
IARC_TP53; 962
IARC_TP53; 3944
Entry history
Entry creation06-Jun-2012
Last entry update19-Dec-2024
Version number18