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Cellosaurus AM-3 (CVCL_A5XS)

[Text version]
Cell line name AM-3
Accession CVCL_A5XS
Resource Identification Initiative To cite this cell line use: AM-3 (RRID:CVCL_A5XS)
Comments Population: Japanese.
Genetic integration: Method=Transduction; Gene=HGNC; HGNC:1582; CCND1.
Genetic integration: Method=Transduction; Gene=HGNC; HGNC:1773; CDK4 (Note=With p.Arg24Cys).
Genetic integration: Method=Transduction; Gene=HGNC; HGNC:11730; TERT.
Genetic integration: Method=Transduction; Gene=HGNC; HGNC:11998; TP53 (Note=With p.Met1_Ala159del).
Derived from site: In situ; Bone, jaw, mandible; UBERON=UBERON_0001684.
Cell type: Ameloblast; CL=CL_0000059.
Disease Follicular ameloblastoma (NCIt: C27397)
Ameloblastoma (ORDO: Orphanet_314419)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling Age unspecified
Category Telomerase immortalized cell line
Publications

PubMed=23706918; DOI=10.1016/j.oooo.2013.03.005
Kibe T., Fuchigami T., Kishida M., Iijima M., Ishihata K., Hijioka H., Miyawaki A., Semba I., Nakamura N., Kiyono T., Kishida S.
A novel ameloblastoma cell line (AM-3) secretes MMP-9 in response to Wnt-3a and induces osteoclastogenesis.
Oral Surg. Oral Med. Oral Pathol. Oral Radiol. 115:780-788(2013)

PubMed=32348439; DOI=10.1590/1678-7757-2019-0558; PMCID=PMC7185982
Fuchigami T., Suzuki H., Yoshimura T., Kibe T., Chairani E., Kiyono T., Kishida M., Kishida S., Nakamura N.
Ameloblastoma cell lines derived from different subtypes demonstrate distinct developmental patterns in a novel animal experimental model.
J. Appl. Oral Sci. 28:e20190558.1-e20190558.7(2020)

PubMed=36452176; DOI=10.1016/j.mbplus.2022.100125; PMCID=PMC9703037
Bakkalci D., Abdullah Zubir A.Z., Khurram S.A., Pape J., Heikinheimo K., Fedele S., Cheema U.
Modelling stromal compartments to recapitulate the ameloblastoma tumour microenvironment.
Matrix Biol. Plus 16:100125.1-100125.13(2022)

Cross-references
Encyclopedic resources Wikidata; Q107113354
Entry history
Entry creation20-May-2021
Last entry update10-Apr-2025
Version number8