Cellosaurus cell line Wilms8 (CVCL

Cellosaurus Wilms8 (CVCL_A5SJ)

[Text version]

Cell line name

Wilms8

Accession

CVCL_A5SJ

Resource Identification Initiative

To cite this cell line use: Wilms8 (RRID:CVCL_A5SJ)

Comments

Population: Caucasian.
Omics: Deep exome analysis.
Derived from site: In situ; Kidney; UBERON=UBERON_0002113.

Sequence variations

Mutation; HGNC; HGNC:2514; CTNNB1; Simple; p.Ser45Ala (c.133T>G); ClinVar=VCV000376241; Zygosity=Heterozygous (PubMed=33379206).
Mutation; HGNC; HGNC:12796; WT1; Simple; p.Arg390Ter (c.1168C>T) (p.Arg463Ter, c.1387C>T); ClinVar=VCV000003494; Zygosity=Homozygous (PubMed=33379206).

Disease

Kidney Wilms tumor (NCIt: C40407)
Nephroblastoma (ORDO: Orphanet_654)

Species of origin

Homo sapiens (Human) (NCBI Taxonomy: 9606)

Sex of cell

Male

Age at sampling

Category

Finite cell line

STR profile

Source(s): CLS=300416; PubMed=33379206

Markers:

Amelogenin	X,Y
CSF1PO	11,12
D3S1358	16,17,18 (CLS=300416) 16,18 (PubMed=33379206)
D5S818	12,13
D7S820	8,10
D8S1179	8,13
D13S317	8,9
D16S539	13
D18S51	12
D21S11	29,33.2
FGA	20,21
Penta D	10,12
Penta E	12,17
TH01	8
TPOX	8,9
vWA	18

Publications

PubMed=33379206; DOI=10.3390/cancers13010060; PMCID=PMC7801943
Royer-Pokora B., Busch M.A., Tenbusch S., Schmidt M., Beier M., Woods A.D., Thiele H., Mora J.
Comprehensive biology and genetics compendium of Wilms tumor cell lines with different WT1 mutations.
Cancers (Basel) 13:60.1-60.21(2021)

Cross-references

Cell line collections (Providers)

CLS; 300416

Encyclopedic resources

Wikidata; Q107117474

Entry history

Entry creation

20-May-2021

Last entry update

19-Dec-2024

Version number