ID   Wilms8
AC   CVCL_A5SJ
DR   CLS; 300416
DR   Wikidata; Q107117474
RX   PubMed=33379206;
CC   Population: Caucasian.
CC   Sequence variation: Mutation; HGNC; HGNC:2514; CTNNB1; Simple; p.Ser45Ala (c.133T>G); ClinVar=VCV000376241; Zygosity=Heterozygous (PubMed=33379206).
CC   Sequence variation: Mutation; HGNC; HGNC:12796; WT1; Simple; p.Arg390Ter (c.1168C>T) (p.Arg463Ter, c.1387C>T); ClinVar=VCV000003494; Zygosity=Homozygous (PubMed=33379206).
CC   Omics: Deep exome analysis.
CC   Derived from site: In situ; Kidney; UBERON=UBERON_0002113.
ST   Source(s): CLS=300416; PubMed=33379206
ST   Amelogenin: X,Y
ST   CSF1PO: 11,12
ST   D13S317: 8,9
ST   D16S539: 13
ST   D18S51: 12
ST   D21S11: 29,33.2
ST   D3S1358: 16,17,18 (CLS=300416)
ST   D3S1358: 16,18 (PubMed=33379206)
ST   D5S818: 12,13
ST   D7S820: 8,10
ST   D8S1179: 8,13
ST   FGA: 20,21
ST   Penta D: 10,12
ST   Penta E: 12,17
ST   TH01: 8
ST   TPOX: 8,9
ST   vWA: 18
DI   NCIt; C40407; Kidney Wilms tumor
DI   ORDO; Orphanet_654; Nephroblastoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
AG   8M
CA   Finite cell line
DT   Created: 20-05-21; Last updated: 19-12-24; Version: 7
//
RX   PubMed=33379206; DOI=10.3390/cancers13010060; PMCID=PMC7801943;
RA   Royer-Pokora B., Busch M.A., Tenbusch S., Schmidt M., Beier M.,
RA   Woods A.D., Thiele H., Mora J.;
RT   "Comprehensive biology and genetics compendium of Wilms tumor cell
RT   lines with different WT1 mutations.";
RL   Cancers (Basel) 13:60.1-60.21(2021).
//