Cellosaurus A549-hACE2-TMPRSS2 (CVCL_A5KB)
| Cell line name | A549-hACE2-TMPRSS2 |
|---|---|
| Accession | CVCL_A5KB |
| Resource Identification Initiative | To cite this cell line use: A549-hACE2-TMPRSS2 (RRID:CVCL_A5KB) |
| Comments | Group: SARS-CoV-2 research cell line. Population: Caucasian. Virology: Highly susceptible to infection by SARS coronavirus 2 (SARS-CoV-2) (COVID-19) and/or spike-pseudotyped lentiviral particles (InvivoGen). Genetic integration: Method=Transfection/transduction; Gene=HGNC; HGNC:13557; ACE2. Genetic integration: Method=Transfection/transduction; Gene=HGNC; HGNC:11876; TMPRSS2. Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P00557; Escherichia coli hygromycin-B 4-O-kinase (hph) (HygR). Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P13249; S.alboniger pac (PuroR). Derived from site: In situ; Lung; UBERON=UBERON_0002048. |
| Sequence variations |
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| Disease | Lung adenocarcinoma (NCIt: C3512) |
| Species of origin | Homo sapiens (Human) (NCBI Taxonomy: 9606) |
| Hierarchy | Parent: CVCL_A5KA (A549-hACE2 [Invivogen]) |
| Sex of cell | Male |
| Age at sampling | 58Y |
| Category | Cancer cell line |
| Web pages | https://www.invivogen.com/a549-ace2-tmprss2-cells |
| Cross-references | |
| Cell line databases/resources | cancercelllines; CVCL_A5KB |
| Encyclopedic resources | Wikidata; Q107113337 |
| Entry history | |
| Entry creation | 20-May-2021 |
| Last entry update | 19-Dec-2024 |
| Version number | 9 |