Cellosaurus Huh7.93 (CVCL_A5AV)
Cell line name | Huh7.93 |
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Synonyms | Huh7.TA61.93 |
Accession | CVCL_A5AV |
Resource Identification Initiative | To cite this cell line use: Huh7.93 (RRID:CVCL_A5AV) |
Comments | Population: Japanese. Virology: Expresses a hepatitis B virus (HBV) subtype AYW genome under the control of a tetracycline transactivator (tTA) protein, a fusion of tetR with the activation domain of HSV-1 VP16. Transcription of HBV pre-genomic RNA is induced upon doxycycline removal from the culture medium, leading to capsid assembly and DNA synthesis (PubMed=16935386). Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P04483; Escherichia coli Tn10 tetR. Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P06492; Human herpesvirus 1 VP16 (UL28) (Note=With p.Met1_Arg360del). Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P00557; Escherichia coli hygromycin-B 4-O-kinase (hph) (HygR). Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P00552; Transposon Tn5 neo. Derived from site: In situ; Liver; UBERON=UBERON_0002107. |
Sequence variations |
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Disease | Adult hepatocellular carcinoma (NCIt: C7956) Adult hepatocellular carcinoma (ORDO: Orphanet_210159) |
Species of origin | Homo sapiens (Human) (NCBI Taxonomy: 9606) |
Hierarchy | Parent: CVCL_0336 (Huh-7) |
Sex of cell | Male |
Age at sampling | 57Y |
Category | Cancer cell line |
Publications | PubMed=16935386; DOI=10.1016/j.jhep.2006.05.019 |
Cross-references | |
Cell line databases/resources | cancercelllines; CVCL_A5AV |
Encyclopedic resources | Wikidata; Q107115398 |
Entry history | |
Entry creation | 20-May-2021 |
Last entry update | 10-Sep-2024 |
Version number | 8 |